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dc.contributor.author
Shaidullina, Aisylu
dc.contributor.author
Harms, Alexander
dc.date.accessioned
2023-03-21T08:51:11Z
dc.date.available
2023-03-19T20:45:57Z
dc.date.available
2023-03-21T08:51:11Z
dc.date.issued
2022-10
dc.identifier.issn
0966-842X
dc.identifier.other
10.1016/j.tim.2022.08.009
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/603820
dc.description.abstract
Toxin–antitoxin systems can defend bacteria against phages by shutting down infected cells, but the links between their molecular mechanisms and biological functions have remained underexplored. LeRoux et al. now show how the DNA-targeting ADP-ribosylation activity of DarTG impairs phage replication but is overcome by dedicated viral inhibitors and evolved tolerance.
en_US
dc.language.iso
en
en_US
dc.publisher
Cell Press
en_US
dc.subject
Toxin–antitoxin system
en_US
dc.subject
Bacterial immunity
en_US
dc.subject
Bacteriophage
en_US
dc.subject
Antiviral defense
en_US
dc.subject
ADP-ribosylation
en_US
dc.title
Antiviral death punch by ADP-ribosylating bacterial toxins
en_US
dc.type
Other Journal Item
dc.date.published
2022-08-18
ethz.journal.title
Trends in Microbiology
ethz.journal.volume
30
en_US
ethz.journal.issue
10
en_US
ethz.journal.abbreviated
Trends Microbiol.
ethz.pages.start
920
en_US
ethz.pages.end
921
en_US
ethz.notes
Spotlight.
en_US
ethz.publication.place
Cambridge, MA
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::02701 - Inst.f. Lebensmittelwiss.,Ernährung,Ges. / Institute of Food, Nutrition, and Health::09807 - Harms, Alexander / Harms, Alexande
en_US
ethz.date.deposited
2023-03-19T20:45:57Z
ethz.source
FORM
ethz.eth
no
en_US
ethz.availability
Metadata only
en_US
ethz.rosetta.installDate
2023-03-21T08:51:12Z
ethz.rosetta.lastUpdated
2024-02-02T21:14:03Z
ethz.rosetta.versionExported
true
ethz.COinS
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