- Journal Article
Glycosylations are notoriously difficult reactions that require extensive optimization regarding the type of anomeric leaving group, solvent, reaction temperature, and reaction time. Described is the use of a silicon‐based microreactor to screen reaction conditions and to scale‐up synthetic procedures. For the first time, glycosyl phosphates were employed in a microreactor. The optimized reaction conditions were successfully transferred to a batch process. © 2007 Verlag Helvetica Chimica Acta Show more
Journal / seriesHelvetica Chimica Acta
Pages / Article No.
PublisherVerlag Helvetica Chimica Acta
SubjectMicroreactor; Glycosylation; Continuous flow; Reaction optimization
Organisational unit03638 - Seeberger, Peter
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