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dc.contributor.author
Bozuyuk, Ugur
dc.contributor.author
Ozturk, Hakancan
dc.contributor.author
Sitti, Metin
dc.date.accessioned
2024-02-05T13:28:13Z
dc.date.available
2024-02-05T13:28:13Z
dc.date.issued
2023-09
dc.identifier.issn
2640-4567
dc.identifier.other
10.1002/aisy.202300099
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/657760
dc.identifier.doi
10.3929/ethz-b-000617158
dc.description.abstract
Surface microrollers have emerged as a promising microrobotic platform for navigation in the circulatory system as future drug/gene delivery applications. The circulatory system comprises various vessels with different dimensions, blood flow velocities, and flow regimes. Therefore, the performance of surface microrollers would vary in blood vessels. Herein, the performance of surface microrollers, with diameters between 5 and 50 mu m, inside vessels of the systemic circulation including veins, venules, capillaries, arterioles, and arteries is investigated with computational fluid dynamics simulations. The simulation environment consists of a simplified fluid with the viscosity and density of blood, without red blood cells, in a cylindrical pipe. The microrollers demonstrate successful upstream locomotion ability in veins and partially in arteries but fail to perform in smaller blood vessels due to significant confinement and flow effects. Overall, the results presented here establish a preliminary result for the future in vivo use of surface microrollers.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Wiley-VCH
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
cardiovascular system
en_US
dc.subject
circulatory system
en_US
dc.subject
computational fluid dynamics
en_US
dc.subject
medical microrobots
en_US
dc.subject
microparticles
en_US
dc.subject
microrobotics
en_US
dc.subject
surface microrollers
en_US
dc.title
Microrobotic Locomotion in Blood Vessels: A Computational Study on the Performance of Surface Microrollers in the Cardiovascular System
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2023-06-04
ethz.journal.title
Advanced Intelligent Systems
ethz.journal.volume
5
en_US
ethz.journal.issue
9
en_US
ethz.journal.abbreviated
Adv. Intell. Syst.
ethz.pages.start
2300099
en_US
ethz.size
12 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Weinheim
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02140 - Dep. Inf.technologie und Elektrotechnik / Dep. of Inform.Technol. Electrical Eng.::02631 - Institut für Biomedizinische Technik / Institute for Biomedical Engineering::09726 - Sitti, Metin (ehemalig) / Sitti, Metin (former)
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02140 - Dep. Inf.technologie und Elektrotechnik / Dep. of Inform.Technol. Electrical Eng.::02631 - Institut für Biomedizinische Technik / Institute for Biomedical Engineering::09726 - Sitti, Metin (ehemalig) / Sitti, Metin (former)
ethz.date.deposited
2023-06-17T03:38:30Z
ethz.source
BATCH
ethz.source
WOS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2024-02-05T13:28:16Z
ethz.rosetta.lastUpdated
2024-02-05T13:28:16Z
ethz.rosetta.exportRequired
true
ethz.rosetta.versionExported
true
dc.identifier.olduri
http://hdl.handle.net/20.500.11850/617158
dc.identifier.olduri
http://hdl.handle.net/20.500.11850/657344
dc.identifier.olduri
http://hdl.handle.net/20.500.11850/657357
ethz.COinS
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