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dc.contributor.author
Adamo, Roberto
dc.contributor.author
Nilo, Alberto
dc.contributor.author
Castagner, Bastien
dc.contributor.author
Boutureira, Omar
dc.contributor.author
Berti, Francesco
dc.contributor.author
Bernardes, Gonçalo J.L.
dc.date.accessioned
2019-06-18T15:37:42Z
dc.date.available
2017-06-10T19:41:47Z
dc.date.available
2019-06-18T15:37:42Z
dc.date.issued
2013-08-01
dc.identifier.issn
2041-6520
dc.identifier.issn
2041-6539
dc.identifier.other
10.1039/c3sc50862e
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/70002
dc.identifier.doi
10.3929/ethz-b-000070002
dc.description.abstract
Primary examples in vaccine design have shown good levels of carbohydrate-specific antibody generation when raised using extracted or fully synthetic capsular polysaccharide glycans covalently coupled to a protein carrier. Herein, we cover recent clinical developments of carbohydrate-based vaccines and describe how novel cutting-edge methodology for the total synthesis of oligosaccharides and for the precise placement of carbohydrates at pre-determined sites within a protein may be used to further improve the safety and efficacy of glycovaccines.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Royal Society of Chemistry
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/3.0/
dc.title
Synthetically defined glycoprotein vaccines: current status and future directions
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 3.0 Unported
dc.date.published
2013-05-07
ethz.journal.title
Chemical Science
ethz.journal.volume
4
en_US
ethz.journal.issue
8
en_US
ethz.journal.abbreviated
Chem. sci.
ethz.pages.start
2995
en_US
ethz.pages.end
3008
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.nebis
006104946
ethz.publication.place
Cambridge
en_US
ethz.publication.status
published
en_US
ethz.date.deposited
2017-06-10T19:43:59Z
ethz.source
ECIT
ethz.identifier.importid
imp593650d7e880636892
ethz.ecitpid
pub:110883
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2017-07-18T08:53:32Z
ethz.rosetta.lastUpdated
2019-06-18T15:37:54Z
ethz.rosetta.versionExported
true
ethz.COinS
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