Dose optimization approach to fast X-ray microtomography of the lung alveoli
- Journal Article
Rights / licenseCreative Commons Attribution 2.0 UK: England & Wales
A basic prerequisite for in vivo X-ray imaging of the lung is the exact determination of radiation dose. Achieving resolutions of the order of micrometres may become particularly challenging owing to increased dose, which in the worst case can be lethal for the imaged animal model. A framework for linking image quality to radiation dose in order to optimize experimental parameters with respect to dose reduction is presented. The approach may find application for current and future in vivo studies to facilitate proper experiment planning and radiation risk assessment on the one hand and exploit imaging capabilities on the other. Show more
Journal / seriesJournal of Applied Crystallography
Pages / Article No.
SubjectDose optimization; Radiation dose; X-ray microtomography; Lung aveoli
Organisational unit03817 - Stampanoni, Marco F.M. / Stampanoni, Marco F.M.
135550 - In-vivo study of lung physiology with sub-second X-ray tomographic microscopy (SNF)
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