DRUG RESISTANCE (PHARMACOLOGY); HUMAN RETROVIRUSES + HIV VIRUSES (VIROLOGY); MOLECULAR EVOLUTION (BIOLOGICAL EVOLUTION); PLEIOTROPIE (GENETIK); EPISTASE (GENETIK); ANTI-AIDS DRUGS; MENSCHLICHE RETROVIREN + HIV-VIREN (VIROLOGIE); ARZNEIMITTELRESISTENZ (PHARMAKOLOGIE); ADAPTATION (BIOLOGICAL EVOLUTION); MOLEKULARE EVOLUTION (BIOLOGISCHE EVOLUTION); MODELLRECHNUNG UND SIMULATION IN DER BIOLOGIE; GENETISCHE POPULATIONSDYNAMIK; VIRENÜBERTRAGUNG (VIROLOGIE); ADAPTATION (BIOLOGISCHE EVOLUTION); TRANSMISSION OF VIRUSES (VIROLOGY); EPISTASIS (GENETICS); GENETIC POPULATION DYNAMICS; BIERHEFE (MIKROBIOTECHNOLOGIE); MEDIKAMENTE ZUR BEHANDLUNG VON AIDS; BREWERS YEAST (MICROBIOTECHNOLOGY); PLEIOTROPY (GENETICS); MATHEMATICAL MODELING AND SIMULATION IN BIOLOGY