- Journal Article
Rights / licenseIn Copyright - Non-Commercial Use Permitted
The I-SMB process is one of the modifications to the standard SMB process that has been demonstrated both theoretically and experimentally to exhibit rather competitive performance (Katsuo and Mazzotti in J Chromatogr A 1217:1354, 2010a, 3067, 2010b; Katsuo et al. in J Chromatogr A 1218:9345, 2011). This work aims at showing that also the I-SMB process can be controlled and optimized by using the optimizing on-line controller developed at ETH Zurich for the standard SMB process (Erdem et al. in Ind Eng Chem Res 43:405, 2004a, 3895, 2004b; Grossmann et al. in Adsorption 14:423, 2008, AIChE J 54:1942008). This is achieved by using a virtual I-SMB unit based on a detailed model of the process; past experience with the on-line controller shows that the controller’s behavior on a virtual platform is essentially the same as in laboratory experiments. Show more
Journal / seriesAdsorption
Pages / Article No.
SubjectSimulated moving bed chromatography; I-SMB; Separation of enantiomers; Troger's base; On-line optimizing control
Organisational unit03484 - Mazzotti, Marco / Mazzotti, Marco
NotesIt was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
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