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dc.contributor.author
Davlatmamadova, Mohbegim
dc.contributor.author
Karimova, Gulzira
dc.contributor.author
Jean-Richard, Vreni
dc.contributor.author
Zimmermann, Michael B.
dc.contributor.author
Wyss, Kaspar
dc.contributor.author
Matthys, Barbara
dc.date.accessioned
2023-07-05T08:29:17Z
dc.date.available
2017-06-11T01:40:42Z
dc.date.available
2023-07-05T08:29:17Z
dc.date.issued
2013-11-02
dc.identifier.issn
1472-6823
dc.identifier.other
10.1186/1472-6823-13-50
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/76469
dc.identifier.doi
10.3929/ethz-b-000076469
dc.description.abstract
Background: Iodine deficiency affects nearly 1.9 billion people worldwide, but it can be prevented by salt iodization. This cross-sectional survey assessed current iodine status, iodized salt coverage and risk factors for goitre among schoolchildren in South Tajikistan. Methods: Ten primary schools in four districts in South Tajikistan were randomly selected. In schoolchildren aged 7 to 11 years, a spot urine sample was collected for measurement of urinary iodine, dried blood spots were collected for measurement of thyroglobulin, and goitre was assessed by palpation. Iodine content of salt samples and local selling points was determined by coloration using rapid test kits and titration method. Results: Of 623 schoolchildren enrolled, complete data was obtained from 589. The overall median urinary iodine concentration (UIC) was 51.2 μg/L indicating mild-to-moderate iodine deficiency. Among all children, 46.6% (95% Confidence Interval (CI) = 42.4%-50.6%) of children were found to be goitrous (grade 1 goitre: 30.6%, 95% CI = 26.9%-34.5%; grade 2 goitre: 16.0%, 95% CI = 13.1%-19.2%). The risk factor for goitre remaining significant in the multivariable logistic regression model was ‘buying salt once a month’ (OR = 2.89, 95% CI = 1.01-8.22) and ‘buying salt once every six months’ (OR = 2.26, 95% CI = 1.01-5.04) compared to ‘buying salt every one or two weeks’. The overall median thyroglobulin concentration was elevated at 13.9 μg/L. Of the salt samples from households and selling points, one third were adequately iodised, one third insufficiently and one third were not iodised. Conclusion: Iodine deficiency remains a serious health issue among children in southern Tajikistan. There is a persisting high prevalence of goitre, elevated thyroglobulin and low UIC despite interventions implemented by Tajikistan and international partners. Quality control of salt iodine content needs to be improved. Continued efforts to raise awareness of the health effects of iodine deficiency are needed to increase consumer demand for iodised salt.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
BioMed Central
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/2.0/
dc.subject
Iodine status
en_US
dc.subject
Goitre
en_US
dc.subject
Risk factors for goitre
en_US
dc.subject
Urinary iodine concentration
en_US
dc.subject
Thyroglobulin concentration
en_US
dc.subject
Salt iodization
en_US
dc.subject
Schoolchildren
en_US
dc.subject
Tajikistan
en_US
dc.title
Iodine nutritional status and risk factors for goitre among schoolchildren in South Tajikistan
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 2.0 Generic
ethz.journal.title
BMC Endocrine Disorders
ethz.journal.volume
13
en_US
ethz.journal.abbreviated
BMC endocr. disord.
ethz.pages.start
50
en_US
ethz.size
13 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.publication.place
London
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::02701 - Inst.f. Lebensmittelwiss.,Ernährung,Ges. / Institute of Food, Nutrition, and Health::03957 - Zimmermann, Michael Bruce (emeritus) / Zimmermann, Michael Bruce (emeritus)
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::02701 - Inst.f. Lebensmittelwiss.,Ernährung,Ges. / Institute of Food, Nutrition, and Health::03957 - Zimmermann, Michael Bruce (emeritus) / Zimmermann, Michael Bruce (emeritus)
ethz.date.deposited
2017-06-11T01:41:53Z
ethz.source
ECIT
ethz.identifier.importid
imp593651570cc3039009
ethz.ecitpid
pub:120794
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2017-07-19T12:15:57Z
ethz.rosetta.lastUpdated
2024-02-03T01:11:25Z
ethz.rosetta.versionExported
true
ethz.COinS
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