Mutation of Threonine 34 in Mouse Podoplanin-Fc Reduces CLEC-2 Binding and Toxicity in Vivo While Retaining Anti-lymphangiogenic Activity

Bianchi, Roberta; Fischer, Eliane; Yuen, Don; Ernst, Ellen; Ochsenbein, Alexandra M.; Chen, Lu; Otto Vivianne I.; Detmar, Michael

doi:10.1074/jbc.M114.550525

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Author

Ochsenbein, Alexandra M.

Date

2014-07-25

Type

Journal Article

Citations

Cited 7 times in Web of Science

Cited 7 times in Scopus

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yes

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Publication status

published

External links

https://doi.org/10.1074/jbc.M114.550525

Journal / series

Journal of Biological Chemistry

Volume

289(30)

Pages / Article No.

21016 - 21027

Publisher

The American Society for Biochemistry and Molecular Biology

Subject

Glycosylation; Lymphangiogenesis; Mutagenesis; Platelet; Recombinant Protein Expression; CLEC-2; Podoplanin

Organisational unit

03683 - Detmar, Michael (emeritus) / Detmar, Michael (emeritus)

Notes

Received 15 January 2014, Revision received 20 May 2014.

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Citations

Cited 7 times in Web of Science

Cited 7 times in Scopus

ETH Bibliography

yes

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Mutation of Threonine 34 in Mouse Podoplanin-Fc Reduces CLEC-2 Binding and Toxicity in Vivo While Retaining Anti-lymphangiogenic Activity Mendeley CSV RIS BibTeX

Mutation of Threonine 34 in Mouse Podoplanin-Fc Reduces CLEC-2 Binding and Toxicity in Vivo While Retaining Anti-lymphangiogenic Activity

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