Mutation of Threonine 34 in Mouse Podoplanin-Fc Reduces CLEC-2 Binding and Toxicity in Vivo While Retaining Anti-lymphangiogenic Activity

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Author
Bianchi, Roberta
Fischer, Eliane
Yuen, Don
Ernst, Ellen
Ochsenbein, Alexandra M.
Chen, Lu
Otto Vivianne I.
Detmar, Michael
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Date
2014-07-25
Type
  • Journal Article
Publication status
published
External links
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Journal / series
The Journal of Biological Chemistry
Volume
289(30)
Pages
21016 - 21027
Publisher
The American Society for Biochemistry and Molecular Biology
Subject
Glycosylation; Lymphangiogenesis; Mutagenesis; Platelet; Recombinant Protein Expression; CLEC-2; Podoplanin
Organisational unit
03683 - Detmar, Michael
Notes
Received 15 January 2014, Revision received 20 May 2014.
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