Alexander, Helen K.
Martin, Oliver Y.Show all
- Journal Article
Rights / licenseCreative Commons Attribution 4.0 International
Evolutionary responses that rescue populations from extinction when drastic environmental changes occur can be friend or foe. The field of conservation biology is concerned with the survival of species in deteriorating global habitats. In medicine, in contrast, infected patients are treated with chemotherapeutic interventions, but drug resistance can compromise eradication of pathogens. These contrasting biological systems and goals have created two quite separate research communities, despite addressing the same central question of whether populations will decline to extinction or be rescued through evolution. We argue that closer integration of the two fields, especially of theoretical understanding, would yield new insights and accelerate progress on these applied problems. Here, we overview and link mathematical modelling approaches in these fields, suggest specific areas with potential for fruitful exchange, and discuss common ideas and issues for empirical testing and prediction. Show more
Journal / seriesEvolutionary Applications
Pages / Article No.
Subjectdrug resistance; eco‐evolutionary feedback; environmental change; experimental evolution; infectious disease; mathematical model; spatiotemporal heterogeneity; standing genetic variation
Organisational unit03584 - Bonhoeffer, Sebastian / Bonhoeffer, Sebastian
03330 - Schmid-Hempel, Paul
137514 - Evolutionary Conflicts and their Impact on Speciation (follow-up) (SNF)
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