Electrostatic transition state stabilization rather than reactant destabilization provides the chemical basis for efficient chorismate mutase catalysis

Thumbnail
Metadata only
Author
Burschowsky, Daniel
van Eerde, André
Ökvist, Mats
Kienhöfer, Alexander
Kast, Peter
Hilvert, Donald
Krengel, Ute
Show all
Date
2014-12
Type
  • Journal Article
Publication status
published
External links
Search via SFX
Journal / series
Proceedings of the National Academy of Sciences of the United States of America
Volume
111(49)
Pages / Article No.
17516 - 17521
Subject
Pericyclic reaction; Catalysis; Enzyme mechanism; Near attack; Conformation; X-ray crystal structures; Escherichia-coli mutase; Enzyme catalysis; Bacillus-subtilis; Active-site; Macromolecular crystallography; Claisen rearrangement; Prephenate reaction; Antibody catalysis; Protein-structure; Mechanism
Organisational unit
08816 - Kast, Peter (Tit.-Prof.)  
03492 - Hilvert, Donald / Hilvert, Donald  
Notes
.
More
Show all metadata
Citations
Cited 9 times in Web of Science
ETH Bibliography
yes
Altmetrics