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dc.contributor.author
Vijaykrishna, Dhanasekaran
dc.contributor.author
Holmes, Edward C.
dc.contributor.author
Joseph, Udayan
dc.contributor.author
Fourment, Mathieu
dc.contributor.author
Su, Yvonne C.F.
dc.contributor.author
Halpin, Rebecca A.
dc.contributor.author
Lee, Raphael T.C.
dc.contributor.author
Deng, Yi-Mo
dc.contributor.author
Gunalan, Vithiagaran
dc.contributor.author
Lin, Xudong
dc.contributor.author
Stockwell, Timothy B.
dc.contributor.author
Fedorova, Nadia B.
dc.contributor.author
Zhou, Bin
dc.contributor.author
Spirason, Natalie
dc.contributor.author
Kühnert, Denise
dc.contributor.author
Boskova, Veronika
dc.contributor.author
Stadler, Tanja
dc.contributor.author
Costa, Anna-Maria
dc.contributor.author
Dwyer, Dominic E.
dc.contributor.author
Huang, Q. Sue
dc.contributor.author
Jennings, Lance C.
dc.contributor.author
Rawlinson, William
dc.contributor.author
Sullivan, Sheena G.
dc.contributor.author
Hurt, Aeron C.
dc.contributor.author
Maurer-Stroh, Sebastian
dc.contributor.author
Wentworth, David E.
dc.contributor.author
Smith, Gavin J.D.
dc.contributor.author
Barr, Ian G.
dc.date.accessioned
2018-09-10T15:56:52Z
dc.date.available
2017-06-11T16:13:57Z
dc.date.available
2018-09-10T15:56:52Z
dc.date.issued
2015-01
dc.identifier.other
10.7554/eLife.05055
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/98273
dc.identifier.doi
10.3929/ethz-b-000098273
dc.description.abstract
A complex interplay of viral, host, and ecological factors shapes the spatio-temporal incidence and evolution of human influenza viruses. Although considerable attention has been paid to influenza A viruses, a lack of equivalent data means that an integrated evolutionary and epidemiological framework has until now not been available for influenza B viruses, despite their significant disease burden. Through the analysis of over 900 full genomes from an epidemiological collection of more than 26,000 strains from Australia and New Zealand, we reveal fundamental differences in the phylodynamics of the two co-circulating lineages of influenza B virus (Victoria and Yamagata), showing that their individual dynamics are determined by a complex relationship between virus transmission, age of infection, and receptor binding preference. In sum, this work identifies new factors that are important determinants of influenza B evolution and epidemiology.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
eLife Sciences Publications
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.title
The contrasting phylodynamics of human influenza B viruses
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
ethz.journal.title
eLife
ethz.journal.volume
4
en_US
ethz.pages.start
e05055
en_US
ethz.size
23 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.identifier.nebis
007613147
ethz.publication.place
Cambridge
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02060 - Dep. Biosysteme / Dep. of Biosystems Science and Eng.::09490 - Stadler, Tanja / Stadler, Tanja
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02720 - Institut für Integrative Biologie / Institute of Integrative Biology::03584 - Bonhoeffer, Sebastian / Bonhoeffer, Sebastian
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02060 - Dep. Biosysteme / Dep. of Biosystems Science and Eng.::09490 - Stadler, Tanja / Stadler, Tanja
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02720 - Institut für Integrative Biologie / Institute of Integrative Biology::03584 - Bonhoeffer, Sebastian / Bonhoeffer, Sebastian
ethz.date.deposited
2017-06-11T16:14:39Z
ethz.source
ECIT
ethz.identifier.importid
imp593652f0ec8ef13882
ethz.ecitpid
pub:153723
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2017-07-14T22:45:06Z
ethz.rosetta.lastUpdated
2019-01-02T13:51:57Z
ethz.rosetta.versionExported
true
ethz.COinS
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