Microfluidic impedance platform for long-term detection of parasite viability


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Date

2018

Publication Type

Other Conference Item

ETH Bibliography

yes

Citations

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Abstract

Schistosomiasis is a disease, caused by a tropical worm of the genus Schistosoma, which infects millions of people annually. The current gold standard for screening candidate drugs against schistosomiasis is highly labor-intensive and provides limited information on drug efficacy. Here, we present an impedance-based microfluidic platform, capable of monitoring the viability of the parasites during long-term measurements. This device can be used as a pre-screening tool for candidate drug selection and to gain more insights into pharmacodynamics.

Publication status

published

External links

Editor

Book title

22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018)

Journal / series

Volume

Pages / Article No.

2375 - 2376

Publisher

Chemical and Biological Microsystems Society

Event

22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2018)

Edition / version

Methods

Software

Geographic location

Date collected

Date created

Subject

Impedance-based detection; Microfluidics; Drug screening; Schistosoma mansoni

Organisational unit

03684 - Hierlemann, Andreas / Hierlemann, Andreas check_circle

Notes

Poster abstract. Poster presentation on November 13, 2018.

Funding

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