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Contrastive learning of global and local features for medical image segmentation with limited annotations


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Date

2021

Publication Type

Conference Paper

ETH Bibliography

yes

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Abstract

A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to pre-train a neural network with unlabeled data, followed by fine-tuning for a downstream task with limited annotations. Contrastive learning, a particular variant of SSL, is a powerful technique for learning image-level representations. In this work, we propose strategies for extending the contrastive learning framework for segmentation of volumetric medical images in the semi-supervised setting with limited annotations, by leveraging domain-specific and problem-specific cues. Specifically, we propose (1) novel contrasting strategies that leverage structural similarity across volumetric medical images (domain-specific cue) and (2) a local version of the contrastive loss to learn distinctive representations of local regions that are useful for per-pixel segmentation (problem-specific cue). We carry out an extensive evaluation on three Magnetic Resonance Imaging (MRI) datasets. In the limited annotation setting, the proposed method yields substantial improvements compared to other self-supervision and semi-supervised learning techniques. When combined with a simple data augmentation technique, the proposed method reaches within 8\% of benchmark performance using only two labeled MRI volumes for training. The code is made public at https://github.com/krishnabits001/domain_specific_cl.

Publication status

published

Book title

Advances in Neural Information Processing Systems 33

Journal / series

Volume

Pages / Article No.

12546 - 12558

Publisher

Curran

Event

34th Annual Conference on Neural Information Processing Systems (NeurIPS 2020)

Edition / version

Methods

Software

Geographic location

Date collected

Date created

Subject

Organisational unit

09579 - Konukoglu, Ender / Konukoglu, Ender check_circle

Notes

Due to the Coronavirus (COVID-19) the conference was conducted virtually.

Funding

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