Generation of integration-free induced pluripotent stem cell lines from four pediatric ADHD patients
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Author / Producer
Date
2021-05
Publication Type
Journal Article
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yes
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Abstract
Human induced pluripotent stem cell (iPSC) lines have been derived from four male patients with childhood attention-deficit hyperactivity disorder (ADHD). Children and adolescents between the ages 6 and 18 suffering from ADHD were recruited for this work. Isolated keratinocytes or peripheral blood mononuclear cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and c-Myc. © 2021 The Author(s)
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Publication status
published
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Book title
Journal / series
Volume
53
Pages / Article No.
102268
Publisher
Elsevier