Journal: Current Opinion in Virology

Abbreviation

Curr Opin Virol

Publisher

Elsevier

Journal Volumes

ISSN

1879-6257
1879-6265

Description

Filters

2011 - 201972020 - 20223
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Publications 1 - 10 of 10
  • Next generation approaches to study virus entry and infection
    Item type: Journal Article
    Kilcher, Samuel; Mercer, Jason (2014)
    Current Opinion in Virology
  • Late-penetrating viruses
    Item type: Journal Article
    Lozach, Pierre-Yves; Huotari, Jatta; Helenius, Ari (2011)
    Current Opinion in Virology
  • Variation in virus effects on host plant phenotypes and insect vector behavior: What can it teach us about virus evolution?
    Item type: Journal Article
    Mauck, Kerry E. (2016)
    Current Opinion in Virology
  • Quantitative measures of within-host viral genetic diversity
    Item type: Review Article
    Fuhrmann, Lara; Jablonski, Kim Philipp; Beerenwinkel, Niko (2021)
    Current Opinion in Virology
    The genetic diversity of virus populations within their hosts is known to influence disease progression, treatment outcome, drug resistance, cell tropism, and transmission risk, and the study of dynamic changes of genetic heterogeneity can provide insights into the evolution of viruses. Several measures to quantify within-host genetic diversity capturing different aspects of diversity patterns in a sample or population are used, based on incidence, relative frequencies, pairwise distances, or phylogenetic trees. Here, we review and compare several of these measures.
  • Poxvirus host cell entry
    Item type: Journal Article
    Schmidt, Florian Ingo; Bleck, Christopher Karl Ernst; Mercer, Jason (2012)
    Current Opinion in Virology
  • Tissue-resident memory T cells in cytomegalovirus infection
    Item type: Journal Article
    Thom, Jenny Tosca; Oxenius, Annette (2016)
    Current Opinion in Virology
  • Engineering therapeutic phages for enhanced antibacterial efficacy
    Item type: Review Article
    Meile, Susanne; Du, Jiemin; Dunne, Matthew; et al. (2022)
    Current Opinion in Virology
    The alarming rise in antimicrobial resistance coupled with a lack of innovation in antibiotics has renewed interest in the development of alternative therapies to combat bacterial infections. Despite phage therapy demonstrating success in various individual cases, a comprehensive and unequivocal demonstration of the therapeutic potential of phages remains to be shown. The co-evolution of phages and their bacterial hosts resulted in several inherent limitations for the use of natural phages as therapeutics such as restricted host range, moderate antibacterial efficacy, and frequent emergence of phage-resistance. However, these constraints can be overcome by leveraging recent advances in synthetic biology and genetic engineering to provide phages with additional therapeutic capabilities, improved safety profiles, and adaptable host ranges. Here, we examine different ways phages can be engineered to deliver heterologous therapeutic payloads to enhance their antibacterial efficacy and discuss their versatile applicability to combat bacterial pathogens.
  • Editorial overview: Viral immunology before COVID-19
    Item type: Other Journal Item
    Oxenius, Annette; Zajac, Allan J. (2022)
    Current Opinion in Virology
  • Ultra-deep sequencing for the analysis of viral populations
    Item type: Journal Article
    Beerenwinkel, Niko; Zagordi, Osvaldo (2011)
    Current Opinion in Virology
  • Virus entry
    Item type: Other Journal Item
    Helenius, Ari; Moss, Bernard (2013)
    Current Opinion in Virology
Publications 1 - 10 of 10