Noncoding RNAs in disease
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Date
2018-09
Publication Type
Review Article
ETH Bibliography
yes
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Abstract
Noncoding RNAs are emerging as potent and multifunctional regulators in all biological processes. In parallel, a rapidly growing number of studies has unravelled associations between aberrant noncoding RNA expression and human diseases. These associations have been extensively reviewed, often with the focus on a particular microRNA (miRNA) (family) or a selected disease/pathology. In this Mini‐Review, we highlight a selection of studies in order to demonstrate the wide‐scale involvement of miRNAs and long noncoding RNAs in the pathophysiology of three types of diseases: cancer, cardiovascular and neurological disorders. This research is opening new avenues to novel therapeutic approaches.
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published
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Journal / series
Volume
592 (17)
Pages / Article No.
2884 - 2900
Publisher
Wiley
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Date collected
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Subject
long noncoding RNA; microRNA; noncoding RNA
Organisational unit
03760 - Hall, Jonathan / Hall, Jonathan