Synaptic tagging: homeostatic plasticity goes Hebbian
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Date
2022-10-17
Publication Type
Journal Article
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Abstract
Distinct plasticity mechanisms enable neurons to effectively process information also when facing global perturbations in network activity. In this issue of The EMBO Journal, Dubes et al (2022) provide a molecular mechanism whereby individual synapses during periods of chronic inactivity are "tagged" for future strengthening. These results lend further support to the idea that local, nonmultiplicative mechanisms play an important role in homeostatic synaptic plasticity as has been demonstrated for Hebbian-like synaptic plasticity.
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published
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Volume
41 (20)
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Publisher
EMBO Press
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Subject
dendritic spine; homeostatic plasticity; microRNA; synaptic scaling; synaptopodin
Organisational unit
09498 - Schratt, Gerhard / Schratt, Gerhard
09498 - Schratt, Gerhard / Schratt, Gerhard
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Funding
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