Journal: Advances in Nutrition

Abbreviation

Adv. Nutr.

Publisher

Elsevier

Journal Volumes

ISSN

2161-8313
2156-5376

Description

Filters

2024 - 20253
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Publications 1 - 3 of 3
  • Perspective: Peer Evaluation of Recommendations for CONSORT Guidelines for Randomized Controlled Trials in Nutrition
    Item type: Journal Article
    Weaver, Connie; Ahles, Sanne; Murphy, Karen J.; et al. (2024)
    Advances in Nutrition
    Creating effective dietary guidance requires a rigorous evidence base that is predominantly developed from robust clinical trials or large-scale cohort studies, with the quality of the data available depending on the completeness and accuracy of their reporting. An international group of academics from 14 institutions in 12 different countries and on 5 continents, working on behalf of the Federation of European Nutrition Societies within its “Improving Standards in the Science of Nutrition” initiative, reviewed the Consolidated Standards of Reporting Trials (CONSORT) statement checklist as it pertains to nutrition trials. This perspective piece documents the procedure followed to gain input and consensus on the checklist previously published by this group, including its presentation and interrogation at the International Union of Nutritional Sciences International Congress of Nutrition 2022 (IUNS-ICN 22), inputs from a survey of journal editors, and its piloting on 8 nutrition trials of diverse designs. Overall, the initiative has been met with considerable enthusiasm. At IUNS-ICN 22, refinements to our proposal were elicited through a World Café method discussion with participating nutrition scientists. The contributing journal editors provided valuable insights, and the discussion led to the development of a potential tool specific to assess adherence to the proposed nutrition extension checklist. The piloting of the proposed checklist provided evidence from real-life studies that reporting of nutrition trials can be improved. This initiative aims to stimulate further discussion and development of a CONSORT-nutrition-specific extension.
  • Advances in Food-As-Medicine Interventions and Their Impact on Future Food Production, Processing, and Supply Chains
    Item type: Review Article
    Defraeye, Thijs; Bahrami, Flora; Kowatsch, Tobias; et al. (2025)
    Advances in Nutrition
    Food-as-medicine (FAM) is an emerging trend among medical doctors, health insurers, startups, and governmental public-health and nongovernmental organizations. FAM implies using food as a part of an individual's health plan to prevent or help treat acute and chronic health conditions and diseases. We highlight trends and hurdles in the FAM intervention pyramid. Our viewpoint is to indicate how interventions might change the future demand for specific food groups, their transport in supply chains, and the technologies used to process them. On the basis of national guidelines, dietary interventions can help to prevent and treat many diseases, including cardiovascular disease, cancers, type 2 diabetes, and obesity. FAM R&D and services offer more individualized treatments. This is challenging given the interindividual variability and complexity of the body's response to food and related factors, such as dietary habits, genetics, lifestyle, and biosphere. Quantifying health improvements is essential to prove the added value of more individualized FAM interventions compared with adopting a general healthy diet. It is unclear which level of individualization of interventions produces the largest health benefits at the lowest costs for the patient, healthcare system, and climate. FAM interventions can support and complement conventional medical treatment. They will require a shift to producing more health-promoting foods, including whole foods, minimally processed foods, and selected processed foods. The food processing industry and supply chains must adapt to these new scenarios. Auxiliary technologies and methods are enablers, including delivery services, wearable technology, health-monitoring apps, and data-driven consumer behavior analysis.
  • Perspective: Framework for Developing Prediction Equations for Estimating the Absorption and Bioavailability of Nutrients from Foods
    Item type: Journal Article
    Weaver, Connie; Armah, Seth; Bruno, Richard S.; et al. (2025)
    Advances in Nutrition
    Current nutrient intake recommendations, nutritional assessments, and food labeling rely on estimated total nutrient content in foods and dietary supplements. However, the adequacy of nutrient intake depends not only on the total amount consumed but also on the fraction absorbed and utilized by the body. Accurate assessments of nutrient bioavailability require predictive equations or algorithms. This paper outlines a 4-step framework designed to guide researchers in developing such equations. The framework includes: 1) identifying key factors that influence nutrient or bioactive compound bioavailability; 2) conducting a comprehensive literature review of high-quality human studies to inform the development of predictive equations; 3) constructing predictive equations based on these insights; and 4) validate the equation, when feasible, to potentiate translation. This structured approach aims to enhance the accuracy and precision of nutrient bioavailability estimates, address data limitations, and highlight evidence gaps to inform future research and policy on nutrients and bioactive compounds.
Publications 1 - 3 of 3