Quantitative analysis of multiple antibody-ligand interactions in a microchip using fluorescence polarization anisotropy
METADATA ONLY
Loading...
Author / Producer
Date
2013
Publication Type
Other Conference Item
ETH Bibliography
yes
Citations
Altmetric
METADATA ONLY
Data
Rights / License
Abstract
We present a microfluidic device that allows quantitative analysis of protein interactions with fluorescently labeled ligands. Dissociation constants (Kd), binding classes (m) as well as number of binding sites (n) can be determined in the same experiment, even if protein mixtures are present.
Permanent link
Publication status
published
External links
Editor
Book title
17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013)
Journal / series
Volume
Pages / Article No.
500 - 502
Publisher
Chemical and Biological Microsystems Society
Event
17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2013)
Edition / version
Methods
Software
Geographic location
Date collected
Date created
Subject
Protein-ligand interaction; Dissociation constant; Binding studies
Organisational unit
03807 - Dittrich, Petra / Dittrich, Petra
Notes
Poster abstract. Poster presentation on October 28, 2013.