Non-pharmaceutical interventions and epigenetic aging in adults: Protocol for a scoping review
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Date
2024
Publication Type
Journal Article
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yes
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Abstract
Introduction: Aging is the strongest risk factor for most chronic diseases. The rising burden of an aging population and non-communicable diseases (NCDs), contributes to escalating costs for society. Several non-pharmaceutical interventions can lower the risk of NCDs, including common mental disorders (CMDs), and may slow down biological aging, as evidenced by outcome markers such as epigenetic clocks. However, a comprehensive overview of whether and which non-pharmaceutical interventions may impact human epigenetic aging is missing. Synthesizing evidence of interventions on epigenetic aging that can be adopted by a wider population is key to guide healthy aging initiatives and to reduce the burden of NCDs and CMDs. This scoping review will identify and assess non-pharmaceutical interventions aimed to slow down epigenetic aging, including their intervention components, and the mode used for intervention delivery.
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published
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19 (8)
Pages / Article No.
Publisher
PLOS
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02120 - Dep. Management, Technologie und Ökon. / Dep. of Management, Technology, and Ec.
03681 - Fleisch, Elgar / Fleisch, Elgar
03995 - von Wangenheim, Florian / von Wangenheim, Florian