Journal: Pediatrics

Abbreviation

Pediatrics (Evanston)

Publisher

American Academy of Pediatrics

Journal Volumes

ISSN

0031-4005

Description

Filters

2004 - 200922010 - 20161
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Publications 1 - 3 of 3
  • Iron fortification reduces blood lead levels in children in Bangalore, India
    Item type: Journal Article
    Zimmermann, Michael B.; Muthayya, Sumithra; Moretti, Diego; et al. (2006)
    Pediatrics
    OBJECTIVE Chronic lead poisoning and iron deficiency are concentrated in urban children from lower socioeconomic strata, and both impair neurocognitive development. Our study objective was to determine if iron fortification reduces blood lead levels in urban, lead-exposed, iron-deficient children in Bangalore, India. DESIGN, SETTING, AND PARTICIPANTS A randomized, double-blind, controlled school-based feeding trial was done in 5- to 13-year-old iron-deficient children (n = 186). At baseline, a high prevalence of lead poisoning was found in the younger children. Subsequently, all 5- to 9-year-old children participating in the trial (n = 134) were followed to determine if iron fortification would affect their blood lead levels. INTERVENTION Children were dewormed and fed 6 days/week for 16 weeks either an iron-fortified rice meal (∼15 mg of iron per day as ferric pyrophosphate) or an identical control meal without added iron. Feeding was directly supervised and compliance monitored. OUTCOME MEASURES Hemoglobin, serum ferritin, C-reactive protein, transferrin receptor, zinc protoporphyrin, and blood lead concentrations were measured. RESULTS The prevalence of iron deficiency was significantly reduced in the iron group (from 70% to 28%) compared with the control group (76% to 55%). There was a significant decrease in median blood lead concentration in the iron group compared with the control group. The prevalence of blood lead levels ≥10 μg/dL was significantly reduced in the iron group (from 65% to 29%) compared with the control group (68% to 55%). CONCLUSIONS Our findings suggest providing iron in a fortified food to lead-exposed children may reduce chronic lead intoxication. Iron fortification may be an effective and sustainable strategy to accompany environmental lead abatement.
  • The Need for Consistency in 407 Reviews
    Item type: Other Journal Item
    Ross, Lainie (2004)
    Pediatrics
  • Proanorexia communities on social media
    Item type: Journal Article
    Oksanen, Atte; Garcia, David; Räsänen, Pekka (2016)
    Pediatrics
Publications 1 - 3 of 3