Decarboxylative Organocatalyzed Aldol-Type Addition Reaction of Chloroacetate Surrogates
METADATA ONLY
Loading...
Author / Producer
Date
2022-12-02
Publication Type
Journal Article
ETH Bibliography
yes
Citations
Altmetric
METADATA ONLY
Data
Rights / License
Abstract
Chlorinated malonic acid half thioesters were established as chloroacetate surrogates and used in stereoselective organocatalyzed decarboxylative aldol-type additions. Enantioenriched alpha-chloro-beta-hydroxy thioesters were obtained under mild reaction conditions in high yields and allowed for diverse derivatization as highlighted by the synthesis of (+)-prebalamide and (+)-norbalasubramide analogs.
Permanent link
Publication status
published
External links
Editor
Book title
Journal / series
Volume
24 (47)
Pages / Article No.
8683 - 8687
Publisher
American Chemical Society
Event
Edition / version
Methods
Software
Geographic location
Date collected
Date created
Subject
Addition reactions; Aldehydes; Molecular structure; Reaction products; Stereoselectivity
Organisational unit
03940 - Wennemers, Helma / Wennemers, Helma
00002 - ETH Zürich
Notes
Funding
188729 - Bioinspirierte Asymmetrische Katalyse (Fortsetzung 2020) (SNF)
Related publications and datasets
Cites: