Quantification capabilities of N₂ MICAP-MS with solution nebulization and aerosol desolvation


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Date

2024-05-01

Publication Type

Journal Article

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Abstract

The analytical capabilities of a nitrogen-sustained high-power microwave inductively coupled atmospheric-pressure plasma mass spectrometer (N₂ MICAP-MS) were investigated using solution nebulization with and without aerosol desolvation. The reduced solvent load for the desolvated aerosol and the increased aerosol transfer resulted in a signal enhancement of ten times for most elements in samples without a significant amount of dissolved solids. An exception was boron, whose signal decreased by a factor of seven when a desolvator was used. To compare the accuracy, reproducibility, and matrix susceptibility of the N₂ MICAP-MS, the mass fractions of 30 elements were determined in two certified water reference materials using external calibration and standard addition. The results were generally found to agree within 10% of the certified reference values with a maximum deviation of 17% in the case of ⁶⁴Zn. Comparing external calibration and standard addition provided comparable results regardless of the sample introduction method. To assess the extent of matrix effects, multi-element standard solutions were doped with amounts of up to 100 mg kg⁻¹ calcium. This resulted in a signal suppression of up to 30% and 70% for conventional nebulization and aerosol desolvation, respectively. This substantially reduced the improvement in sensitivity observed for the desolvated aerosol. To further investigate the fundamental characteristics of the N₂ MICAP-MS, the plasma gas temperature was estimated using three methods. The determined temperatures for the two most reliable methods were in the range of similar to ∼5000-6000 K and were found to be independent of the sample introduction method and similar to those of an Ar ICP.

Publication status

published

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Volume

39 (5)

Pages / Article No.

1388 - 1397

Publisher

Royal Society of Chemistry

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Edition / version

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Organisational unit

03512 - Günther, Detlef / Günther, Detlef check_circle

Notes

Funding

197224 - New Ion Source Configurations for Discrete Sample Analysis with ICPMS (SNF)

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