Towards clinical-dose grating interferometry breast CT with fused intensity-based iterative reconstruction
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Date
2023-02-27
Publication Type
Journal Article
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yes
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Abstract
X-ray grating interferometry CT (GI-CT) is an emerging imaging modality which provides three complementary contrasts that could increase the diagnostic content of clinical breast CT: absorption, phase, and dark-field. Yet, reconstructing the three image channels under clinically compatible conditions is challenging because of severe ill-conditioning of the tomographic reconstruction problem. In this work we propose to solve this problem with a novel reconstruction algorithm that assumes a fixed relation between the absorption and the phase-contrast channel to reconstruct a single image by automatically fusing the absorption and phase channels. The results on both simulations and real data show that, enabled by the proposed algorithm, GI-CT outperforms conventional CT at a clinical dose.
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published
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Journal / series
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31 (5)
Pages / Article No.
9052 - 9071
Publisher
Optica
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09603 - Alaifari, Rima (ehemalig) / Alaifari, Rima (former)
03817 - Stampanoni, Marco F.M. / Stampanoni, Marco F.M.
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Funding
183568 - GI-BCT - Clinical Grating Interferometry Breast Computed Tomography (SNF)
ETH-12 20-2 - ELISABETH-X: dEep Learning drIven X-ray phaSe contrAst BrEast TomograpHy (ETHZ)
ETH-12 20-2 - ELISABETH-X: dEep Learning drIven X-ray phaSe contrAst BrEast TomograpHy (ETHZ)