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Neueste Publikationen
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Seismic Tomography 2024
(2024)Bulletin of the Seismological Society of AmericaSeismic tomography is the most abundant source of information about the internal structure of the Earth at scales ranging from a few meters to thousands of kilometers. It constrains the properties of active volcanoes, earthquake fault zones, deep reservoirs and storage sites, glaciers and ice sheets, or the entire globe. It contributes to outstanding societal problems related to natural hazards, resource exploration, underground storage, ...Journal Article -
Lesions to the mediodorsal thalamus, but not orbitofrontal cortex, enhance volatility beliefs linked to paranoia
(2024)Cell ReportsBeliefs—attitudes toward some state of the environment—guide action selection and should be robust to variability but sensitive to meaningful change. Beliefs about volatility (expectation of change) are associated with paranoia in humans, but the brain regions responsible for volatility beliefs remain unknown. The orbitofrontal cortex (OFC) is central to adaptive behavior, whereas the magnocellular mediodorsal thalamus (MDmc) is essential ...Journal Article -
Experiments as DTs
(2024)Handbook of Digital TwinsDTs (DTs) have become the buzzword of the decade, permeating research, industry and even governance as indicated by Gartner’s hype measure [47]. At the same time, DTs are highly under-specified and each DT is based on a slightly different conceptualisation. So far, most DTs have focused on the digitalisation of crucial components of a system [18]. More recent work has unveiled a methodology to describe the five core components to construct ...Book Chapter -
Mitochondrial dysfunction results in enhanced adrenal androgen production in H295R cells
(2024)The journal of steroid biochemistry and molecular biologyThe role of mitochondria in steroidogenesis is well established. However, the specific effects of mitochondrial dysfunction on androgen synthesis are not fully understood. In this study, we investigate the effects of various mitochondrial and metabolic inhibitors in H295R adrenal cells and perform a comprehensive analysis of steroid and metabolite profiling. We report that mitochondrial complex I inhibition by rotenone shifts cells toward ...Journal Article -
Dynamics of bistable composite plates
(2024)International Journal of Non-Linear MechanicsNonlinear asymmetric bi-stable composite laminates, characterized by multistable nature and rich dynamics, have seen increased application potential recently. This has necessitated a detailed dynamical analysis of bistable laminates. In this manuscript, the nonlinear behaviour of asymmetric [0n/90n] bistable laminates with free–free boundary conditions is investigated through simulations and experimental observations. A refined 17 degrees ...Journal Article