1. A PRODUCT LIFE CYCLE APPROACH TO MEDICAL DEVICE DEVELOPMENT FOR LOW-RESOURCE SETTINGS - A SYSTEMATIC LITERATURE REVIEW 

   Overhoff, Milena; Lumpe, Thomas S.; Shea, Kristina (2023)

   PROCEEDINGS OF ASME 2023 INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, IDETC-CIE2023, VOL 6

   Rural areas in most of the world lack functional medical devices for essential care. Even though devices exist on the global market, they are often not accessible in low-resource settings (LRS). One evident reason is the high price that many health facilities in rural areas cannot afford. However, even after the initial purchase, an estimated 70-90% of the devices are not operational. The core of this problem is often that the existing ...

   Conference Paper

2. Surface-Functionalized Microgels as Artificial Antigen-Presenting Cells to Regulate Expansion of T Cells 

   Lou, Junzhe; Meyer, Charlotte; Vitner, Einat B.; et al. (2024)

   ADVANCED MATERIALS

   Artificial antigen-presenting cells (aAPCs) are currently used to manufacture T cells for adoptive therapy in cancer treatment, but a readily tunable and modular system can enable both rapid T cell expansion and control over T cell phenotype. Here, it is shown that microgels with tailored surface biochemical properties can serve as aAPCs to mediate T cell activation and expansion. Surface functionalization of microgels is achieved via ...

   Journal Article

3. Simultaneous quantification of terpenes and cannabinoids by reversed-phase LC-APCI-MS/MS in <i>Cannabis sativa</i> L. samples combined with a subsequent chemometric analysis 

   Raeber, Justine; Poetzsch, Michael; Schmidli, Anina; et al. (2024)

   Analytical and Bioanalytical Chemistry

   Cannabis sativa L. has been the most discussed medicinal plant in recent years. In particular, the dynamic shift from a formerly illicit and tightly controlled substance to a plant recognized for both medicinal and recreational purposes has brought C. sativa into the global spotlight. Due to the ongoing international legalization processes, fast and convenient analytical methods for the quality control of C. sativa flowers for medicinal ...

   Journal Article

4. A field experiment to assess barriers to accurate household food waste measurements 

   Merian, Sybilla; O'Sullivan, Kevin; Stockli, Sabrina; et al. (2024)

   Resources, Conservation and Recycling

   The United Nations' sustainable development goals call for a 50 % reduction in global household food waste by 2030, but an accurate measurement method to quantify household food waste has yet to be developed. In a field experiment with 359 households, this study compares standard food waste measurement methods (survey, diary, kitchen caddy) and assesses the barriers to accurate measures. Based on our experimental design, we derive a minimal ...

   Journal Article

5. Early arc crust formation preserved in the Grenadines archipelago, southern Lesser Antilles arc 

   Camejo-Harry, Michal; Melekhova, Elena; Aufrere, Sarah; et al. (2024)

   Royal Society Open Science

   Intra-arc diversity in volcanic activity and composition is ubiquitous, but its underlying causes remain largely unresolved in many settings. In this work, we examine such variability in the Grenadines archipelago, southern Lesser Antilles arc. Here, juxtaposed volcanic centres exhibit eruptive longevities and chemistries distinct from northern counterparts in the same arc. Our goal is to explain this deviation by investigating variations ...

   Journal Article

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