1. Chemical and mRNA-based Cellular Reprogramming to Muscle Progenitor Cells for the Treatment of Muscular Dystrophy 

   Qabrati, Xhem (2024)

   Muscular dystrophies encompass a group of genetic diseases with a wide spectrum of clinical severities. Duchenne muscular dystrophy (DMD) is the most common and debilitating form of dystrophy, causing progressive muscle wasting and premature death due to cardiorespiratory failure. DMD is triggered by mutations in the DMD gene that is needed to stabilize myofibers. Its absence causes perpetuating cycles of myofiber necrosis and muscle ...

   Doctoral Thesis

2. Navigating collaboration for innovation both within and across organizational boundaries: An interaction-centric perspective 

   Varesco Kager, Nora (2024)

   Innovation is crucial for firms’ long-term success, and collaboration within and across organizational boundaries is crucial for innovation, making it important to understand collaboration demands and their navigation. To do so, scholars suggested taking a holistic approach by attending to interactions between relevant elements. Yet, while collaboration elements like tensions, challenges, and success-factors have been described, there ...

   Doctoral Thesis

3. Exposure manipulation strategies for balancing computational efficiency and precision in seismic risk analysis 

   Papadopoulos, Athanasios N.; Roth, Philippe; Danciu, Laurentiu (2024)

   Bulletin of Earthquake Engineering

   Exposure models for regional seismic risk assessment often place assets at the centroids of administrative units for which data are available. At best, a top-down approach is followed, where such data are spatially disaggregated over a denser spatial grid, using proxy datasets such as the distribution of population or the density of night-time lights. The resolution of the spatial grid is either dictated by the resolution of the proxy ...

   Journal Article

4. Investigating the Martian soil at the InSight landing site 

   Delage, Pierre; Caicedo, Bernardo; Golombek, Matt; et al. (2024)

   SOILS AND ROCKS

   The InSight mission is a geophysical mission aimed at better understanding the structure of Mars and of the other rocky planets of the solar system. To do so, a lander accommodating two cameras, a very sensitive seismometer, and a dynamic self -penetrating heat probe nicknamed the mole were placed on the Mars surface by the Instrument Deployment Arm (IDA). Besides geophysical data (which definitely enriched the existing knowledge on the ...

   Journal Article

5. A graph model to describe the network connectivity of trabecular plates and rods 

   Walle, Matthias; Yeritsyan, Diana; Abbasian, Mohammadreza; et al. (2024)

   Frontiers in Bioengineering and Biotechnology

   Introduction: The trabecular network is perceived as a collection of interconnected plate- (P) and rod-like (R) elements. Previous research has highlighted how these elements and their connectivity influence the mechanical properties of bone, yet further work is required to elucidate better the deeply interconnected nature of the trabecular network with distinct element formations conducting forces per their mechanical boundary conditions. ...

   Journal Article

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