1. Reynolds Stress Model Study Comparing the Secondary Currents and Turbulent Flow Characteristics in High-Speed Narrow Open Channel and Duct Flows 

   Kadia, Subhojit; Albayrak, Ismail; Lia, Leif; et al. (2024)

   Journal of Hydraulic Engineering

   This study numerically investigates and compares the secondary currents, velocity dips, turbulence properties, and boundary shear stresses in supercritical narrow open channel flows (OCFs) and in narrow duct flows (DFs) using an updated Launder–Reece–Rodi Reynoldsstress model in OpenFOAM, which was validated previously for supercritical flows using experimental data. Six steady state simulations were performed at a bulk velocity of 2.31 ...

   Journal Article

2. Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB 

   Lampson B.L.; Ramίrez A.S.; Baro M.; et al. (2024)

   Cell

   Nuclear factor κB (NF-κB) plays roles in various diseases. Many inflammatory signals, such as circulating lipopolysaccharides (LPSs), activate NF-κB via specific receptors. Using whole-genome CRISPR-Cas9 screens of LPS-treated cells that express an NF-κB-driven suicide gene, we discovered that the LPS receptor Toll-like receptor 4 (TLR4) is specifically dependent on the oligosaccharyltransferase complex OST-A for N-glycosylation and ...

   Journal Article

3. Digital Twin-Based Cyber-Attack Detection Framework for Cyber-Physical Manufacturing Systems 

   Balta E.C.; Pease M.; Moyne J.; et al. (2024)

   IEEE Transactions on Automation Science and Engineering

   Smart manufacturing (SM) systems utilize run-time data to improve productivity via intelligent decision-making and analysis mechanisms on both machine and system levels. The increased adoption of cyber-physical systems in SM leads to the comprehensive framework of cyber-physical manufacturing systems (CPMS) where data-enabled decision-making mechanisms are coupled with cyber-physical resources on the plant floor. Due to their cyber-physical ...

   Journal Article

4. Strain energy dependent numerical simulation of rock fracture initiation and propagation using soundless cracking demolition agents (SCDA): Effects of SCDA-filled rock joints 

   De Silva V.R.S.; Konietzky H.; Ranjith P.G.; et al. (2024)

   International Journal of Rock Mechanics and Mining Sciences

   Soundless Cracking Demolition Agents (SCDA) are gaining traction as an innovative technique for controlled rock fracturing in applications such as underground energy, mineral extraction, and excavation. This paper presents a novel numerical approach to simulate SCDA-charged rock fracture initiation using the strain energy density of SCDA. This approach eliminates the need for prior knowledge of the peak expansive pressure developed in a ...

   Journal Article

5. The second coefficient of the Alexander polynomial as a satellite obstruction 

   Lewark, Lukas (2024)

   arXiv

   A set P of links is introduced, containing positive braid links as well as arborescent positive Hopf plumbings. Inspired by work of Ito, it is shown that for links in P, the leading and the second coefficient of the Alexander polynomial have opposite sign. It follows that certain satellite links, such as (n,1)-cables, are not in P.

   Working Paper

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