1. Exact global alignment using A* with chaining seed heuristic and match pruning 

   Koerkamp R.G.; Ivanov P. (2024)

   Bioinformatics

   Motivation: Sequence alignment has been at the core of computational biology for half a century. Still, it is an open problem to design a practical algorithm for exact alignment of a pair of related sequences in linear-like time. Results: We solve exact global pairwise alignment with respect to edit distance by using the A* shortest path algorithm. In order to efficiently align long sequences with high divergence, we extend the recently ...

   Journal Article

2. Characterization of genomic variation and its association with complex traits and gene expression in cattle 

   Bhati, Meenu (2024)

   Cattle play a pivotal role in agriculture, providing vital resources such as milk and meat, and have a special cultural significance. Domestication and human mediated selection have led to the diversification of cattle breeds worldwide. In recent decades, genomic technologies, in particular whole genome sequencing, have revolutionised our understanding of the genetic diversity within cattle populations. However, many aspects of their ...

   Doctoral Thesis

3. Observations of root hair patterning in soils: Insights from synchrotron-based X-ray computed microtomography 

   Duddek, Patrick; Papritz, Andreas; Ahmed, Mutez Ali; et al. (2024)

   Plant and Soil

   Background and Aims: Root hair emergence is affected by heterogeneities in water availability in the growth medium. Root hairs preferentially emerge into air, whereas their emergence into water is inhibited. Yet, these results were based either on destructive methods or on roots grown on an agar-air interface. Additionally, there is a lack of knowledge about the spatial distribution of root hairs as hairs elongate radially across the ...

   Journal Article

4. Interannual Variability of Marine Nitrogen Fixation in the Western Tropical Atlantic 

   Härri, Jana; Louchard, Domitille; Gruber, Nicolas (2024)

   Global Biogeochemical Cycles

   N₂ fixation is a central process of the marine nitrogen cycle, yet little is known about how this process varies from year-to-year. Here, we investigate this variability in the Western Tropical Atlantic (WTA), a region where N₂ fixation is prevalent, fueled, in part, by the nutrient input from the Amazon River. We use hindcast simulations from 1983 through 2019 with the Regional Oceanic Modeling System (ROMS) coupled to the Biogeochemical ...

   Journal Article

5. Cutaneous and immune effects of photochemical-based vaccination in mice 

   Kotkowska, Zuzanna K. (2024)

   Vaccination is the medical intervention with perhaps the strongest impact on human health. Conventional vaccines have successfully prevented infectious diseases for more than a century by inducing long-lasting immune responses. Research and development during the last decades have shown that also cancer can be treated by engaging the immune system. However, while the immune system efficiently recognizes foreign protein antigens on pathogens, ...

   Doctoral Thesis

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