Probing the germline-dependence of non-genetic inheritance using artificial insemination in mice
Open access
Datum
2016-01Typ
- Journal Article
ETH Bibliographie
yes
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Abstract
We developed a simple, noninvasive artificial insemination technique to study epigenetic germline inheritance in mice. This technique avoids interfering factors introduced by superovulation, surgery, in vitro culture or mating that can confound the transmission of acquired epigenetic information through the germline. Using a stress model, we demonstrate that our method is suited to test the causal involvement of the male germline in transmitting acquired information from father to offspring. Mehr anzeigen
Persistenter Link
https://doi.org/10.3929/ethz-b-000126817Publikationsstatus
publishedExterne Links
Zeitschrift / Serie
Environmental EpigeneticsBand
Seiten / Artikelnummer
Verlag
Oxford University PressThema
Epigenetic inheritance; Artificial insemination; Germline-dependence; Mice; Transgenerational; SpermOrganisationseinheit
03518 - Mansuy, Isabelle / Mansuy, Isabelle
ETH Bibliographie
yes
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