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The Fictional Addressee of Architecture as a Device for Exploring Post-colonial Culture: The Transformations of the Helleno-centric Approaches
(2019)This postdoctoral research project examines the relationships between architecture’s epistemology within the Greek and international contexts, scrutinizing their interdependences. It is focused on the analysis of three case studies: the travels to Greece of the Villa Medici pensionnaires in the 19th century, the trajectories of the architects of Mataroa, and the different approaches of bridging Helleno-centricism and modernism within the ...Working Paper -
Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow
(2019)bioRxivHere we describe tissue-resident memory B lymphocytes of spleen and bone marrow. Single cell transcriptomes and B cell receptor repertoires identify several exclusive populations of isotype-switched memory B cells (Bsm) in murine spleen and bone marrow, and one interconnected population of 10-20%. A population of marginal zone-like Bsm is located exclusively in the spleen while a novel population of quiescent Bsm is located exclusively ...Working Paper -
psupertime: supervised pseudotime inference for single cell RNA-seq data with sequential labels
(2019)bioRxivSingle cell RNA-seq has been successfully combined with pseudotime inference methods to investigate biological processes which have sequential labels, such as time series studies of development and differentiation. Pseudotime methods developed to date ignore the labels, and where there is substantial variation in the data not associated with the labels (such as cell cycle variation or batch effects), they can fail to find relevant genes. ...Working Paper -
SERA WP7/NA5 - Deliverable 7.4: Towards improvement of site condition indicators
(2019)This report summarizes the research undertaken by ETH in the framework of WP7/NA5 – Task 7.4 of SERA project (“Towards improvement of site characterization indicators”), in collaboration with partners AUTH, INGV, CNRS. We have addressed the broad topic of site condition indicators, or proxies, with a comprehensive work: i) firstly, we have reviewed the state of the art and tracked the present research trends in the use of proxies; ii) ...Report -
Minimisation of surface energy drives apical epithelial organisation and gives rise to Lewis’ law
(2019)bioRxivThe packing of cells in epithelia exhibits striking regularities, regardless of the organism and organ. One of these regularities is expressed in Lewis’ law, which states that the average apical cell area is linearly related to the number of neighbours, such that cells with larger apical area have on average more neighbours. The driving forces behind the almost 100-year old Lewis’ law have remained elusive. We now provide evidence that ...Working Paper -
Aboave-Weaire’s law in epithelia results from an angle constraint in contiguous polygonal lattices
(2019)bioRxivIt has long been noted that the cell arrangements in epithelia, regardless of their origin, exhibit some striking regularities: first, the average number of cell neighbours at the apical side is (close to) six. Second, the average apical cell area is linearly related to the number of neighbours, such that cells with larger apical area have on average more neighbours, a relation termed Lewis’ law. Third, Aboav-Weaire’s (AW) law relates the ...Working Paper -
Architecture's Addressees: Drawing as Investigating Device
(2019)The article examines how the concept of the addressee of architecture has transformed throughout the twentieth century, demonstrating how the mutations of the dominant means of representation in architecture are linked to the evolving significance of the city’s inhabitants. It presents the ways in which the reorientations regarding the dominant modes of representation depend on the transfor-mations of architects’ conceptions of the notion ...Working Paper