Effects of the 1-N-(4-Amino-2S-hydroxybutyryl) and 6′-N-(2-Hydroxyethyl) Substituents on Ribosomal Selectivity, Cochleotoxicity and Antibacterial Activity in the Sisomicin Class of Aminoglycoside Antibiotics
Publikationsstatus
publishedExterne Links
Zeitschrift / Serie
ACS Infectious DiseasesBand
Seiten / Artikelnummer
Verlag
American Chemical SocietyThema
aminoglycosides; structure-activity relationship; minoglycoside-modifying enzymes; ribosomal methyltransferases; cell-free translation assays