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Experimental evaluation of bearingless spinfilter topologies
(2024)Separation and Purification TechnologyRotating filter membranes can increase the long term filtrate flux by efficiently and continuously removing the retained particles on a microfiltration membrane. However, the practical implementation of rotating machinery in high purity applications such as biotechnological manufacturing of proteins raises concerns about the contamination of the process fluids due to submerged bearings and imperfect sealings to the outside environment. ...Journal Article -
Tumor targeted and GSH stimuli-response α‑lactalbumin nanotubes co-delivering doxorubicin and siRNA for cancer therapy
(2024)Journal of Future Foodsα-Lactalbumin (α-lac), a natural food-sourced protein, exhibits high biocompatibility as delivery systems for small bioactive molecules or RNA. However, their potential clinical application as a delivery system is greatly limited due to the lack of targeting to desired tissues, such as tumors. Here, a delivery system/nanocarrier of nanotube (NT) was fabricated by the self-assembly of peptides hydrolyzed from α-lac. Among the loading of ...Journal Article -
Bicycle as a traffic mode
(2024)Journal of Cycling and Micromobility ResearchCities allocate dedicated road space to bicycles in favor of active-mode road users. For urban environments with a mass bicycle volume, bicycle traffic congestion is likely to occur. Hence, a thorough understanding of bicycle traffic flow is necessary for the assessment of cycling infrastructure and the development of traffic management strategies considering cycling efficiency. This study aims to investigate bicycle flow characteristics ...Journal Article -
Comparative study on route choice models for cyclists
(2024)Journal of Cycling and Micromobility ResearchThis paper presents a comparison of different route choice models for cyclists. The data includes approx. 3,700 cycling trajectories. The network is derived based on the Open-Street-Map that contains street-level attribute information. We estimate two path-based and one link-based model. We present descriptive statistics, model results, resulting indicators, and compare different validation approaches. The results reveal important differences ...Journal Article -
Decentralized project delivery on the crypto commons: Conceptualization, governance mechanisms, and future research directions
(2024)Project Leadership and SocietyThis paper presents a first conceptualization for decentralized project delivery through the combination of blockchain technology and common pool resource governance theory, also known as the ”crypto commons”. While previous literature on project delivery models identifies the use of decentralized governance, there is not yet a holistic conceptualization nor a specific overview of governance applications that can be applied. To develop ...Journal Article -
The advancement of artificial intelligence in biomedical research and health innovation: challenges and opportunities in emerging economies
(2024)Globalization and HealthThe advancement of artificial intelligence (AI), algorithm optimization and high-throughput experiments has enabled scientists to accelerate the discovery of new chemicals and materials with unprecedented efficiency, resilience and precision. Over the recent years, the so-called autonomous experimentation (AE) systems are featured as key AI innovation to enhance and accelerate research and development (R&D). Also known as self-driving ...Journal Article -
Bounds to electron spin qubit variability for scalable CMOS architectures
(2024)Nature CommunicationsSpins of electrons in silicon MOS quantum dots combine exquisite quantum properties and scalable fabrication. In the age of quantum technology, however, the metrics that crowned Si/SiO2 as the microelectronics standard need to be reassessed with respect to their impact upon qubit performance. We chart spin qubit variability due to the unavoidable atomic-scale roughness of the Si/SiO2 interface, compiling experiments across 12 devices, and ...Journal Article -
Advances in non-invasive imaging of proteinopathies in animal models of neurodegenerative diseases
(2024)Neural Regeneration ResearchJournal Article -
Mechanical recycling of PET containing mixtures of phosphorus flame retardants
(2024)Journal of Materials Science and TechnologyFlame -retarded polymers, such as polyester textiles and sheets, are attracting attention with regard to their sustainability. Mechanical recycling is currently the most frequently used technique for improving the circularity of plastics. However, one complication of mechanical recycling is associated with the (still) inevitable mixtures of polymers and additives, which can influence material stability and significantly deteriorate the ...Journal Article -
Embedding loose spanning trees in 3-uniform hypergraphs
(2024)Journal of Combinatorial Theory. Series BIn 1995, Komlós, Sárközy and Szemerédi showed that every large n-vertex graph with minimum degree at least (1/2+γ)n contains all spanning trees of bounded degree. We consider a generalization of this result to loose spanning hypertrees in 3-graphs, that is, linear hypergraphs obtained by successively appending edges sharing a single vertex with a previous edge. We show that for all γ and Δ, and n large, every n-vertex 3-uniform hypergraph ...Journal Article