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Modulatory effects of Tabebuia impetiginosa (Lamiales, Bignoniaceae) on doxorubicin-induced somatic mutation and recombination in Drosophila melanogaster
(2009)Genetics and Molecular BiologyThe wing Somatic Mutation and Recombination Test (SMART) in D. melanogaster was used to study genotoxicity of the medicinal plant Tabebuia impetiginosa. Lapachol (naphthoquinone) and β-lapachone (quinone) are the two main chemical constituents of T. impetiginosa. These compounds have several biological properties. They induce apoptosis by generating oxygen-reactive species, thereby inhibiting topoisomerases (I and II) or inducing other ...Journal Article -
Versuche zur Ermüdungsfestigkeit alter Betonstähle
(2009)Beton- und StahlbetonbauJournal Article -
High-field H-1 T-1 and T-2 NMR relaxation time measurements of H2O in homeopathic preparations of quartz, sulfur, and copper sulfate
(2009)NaturwissenschaftenJournal Article -
Toxicity of Tungsten Carbide and Cobalt-Doped Tungsten Carbide Nanoparticles in Mammalian Cells in Vitro
(2009)Environmental Health PerspectivesBackground Tungsten carbide nanoparticles are being explored for their use in the manufacture of hard metals. To develop nanoparticles for broad applications, potential risks to human health and the environment should be evaluated and taken into consideration. Objective We aimed to assess the toxicity of well-characterized tungsten carbide (WC) and cobaltdoped tungsten carbide (WC-Co) nanoparticle suspensions in an array of mammalian ...Journal Article -
Long-term Biomonitoring of Alpine Waters in the Swiss National Park
(2009)eco.mont: Journal on Protected Mountain Areas Research and ManagementThis paper summarizes the initial results from the long-term monitoring program of running and standing waters in a high elevation cirque landscape (Macun Lakes) in the Swiss National Park. The region comprises two contrasting basins with different water sources, a glacier-fed basin and a precipitation-fed basin. Monitoring encompasses annual measures of physico-chemistry of the waters along with samples of macroinvertebrates in midsummer. ...Journal Article -
A Multi-Individual Pharmacokinetic Model Framework for Interpreting Time Trends of Persistent Chemicals in Human Populations
(2009)Environmental Health PerspectivesBa c k g r o u n d: Human milk and blood are monitored to detect time trends of persistent organic pollutants (POPs) in humans. It is current practice to use log-linear regression to fit time series of averaged cross-sectional biomonitoring data, here referred to as cross-sectional trend data (CSTD). O b j e c t i v e: The goals of our study are to clarify the interpretation of half-lives derived from fitting exponential functions to ...Journal Article -
Mid-Pliocene shifts in ocean overturning circulation and the onset of Quaternary-style climates
(2009)Climate of the PastA major tipping point of Earth's history occurred during the mid-Pliocene: the onset of major Northern-Hemisphere Glaciation (NHG) and of pronounced, Quaternary-style cycles of glacial-to-interglacial climates, that contrast with more uniform climates over most of the preceding Cenozoic and continue until today (Zachos et al., 2001). The severe deterioration of climate occurred in three steps between 3.2 Ma (warm MIS K3) and 2.7 Ma (glacial ...Journal Article -
Comparative predictions of discharge from an artificial catchment (Chicken Creek) using sparse data
(2009)Hydrology and Earth System SciencesTen conceptually different models in predicting discharge from the artificial Chicken Creek catchment in North-East Germany were used for this study. Soil texture and topography data were given to the modellers, but discharge data was withheld. We compare the predictions with the measurements from the 6 ha catchment and discuss the conceptualization and parameterization of the models. The predictions vary in a wide range, e.g. with the ...Journal Article