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Community detection in large hypergraphs
(2023)Science AdvancesHypergraphs, describing networks where interactions take place among any number of units, are a natural tool to model many real-world social and biological systems. Here, we propose a principled framework to model the organization of higher-order data. Our approach recovers community structure with accuracy exceeding that of currently available state-of-the-art algorithms, as tested in synthetic benchmarks with both hard and overlapping ...Journal Article -
Electron-Driven Nitration of Unsaturated Hydrocarbons
(2023)Angewandte Chemie. International EditionHerein, we introduce an electrochemically assisted generation of nitryl radicals from ferric nitrate under mild reaction conditions using a simple setup with inexpensive graphite and stainless-steel electrodes. The mechanism of the reaction is supported by detailed spectroscopic and experimental studies. Powered by electricity and driven by electrons, the synthetic diversity of this reaction has been demonstrated through the development ...Journal Article -
Engineering Inflammation-Resistant Cartilage: Bridging Gene Therapy and Tissue Engineering
(2023)Advanced Healthcare MaterialsArticular cartilage defects caused by traumatic injury rarely heal spontaneously and predispose into post-traumatic osteoarthritis. In the current autologous cell-based treatments the regenerative process is often hampered by the poor regenerative capacity of adult cells and the inflammatory state of the injured joint. The lack of ideal treatment options for cartilage injuries motivated the authors to tissue engineer a cartilage tissue ...Journal Article -
Controlling the Strong Metal-Support Interaction Overlayer Structure in Pt/TiO2 Catalysts Prevents Particle Evaporation
(2023)Angewandte Chemie. International EditionPlatinum nanoparticles (NPs) supported by titania exhibit a strong metal-support interaction (SMSI)[1] that can induce overlayer formation and encapsulation of the NP's with a thin layer of support material. This encapsulation modifies the catalyst's properties, such as increasing its chemoselectivity[2] and stabilizing it against sintering.[3] Encapsulation is typically induced during high-temperature reductive activation and can be ...Journal Article -
Machine learning to predict poor school performance in paediatric survivors of intensive care: a population-based cohort study
(2023)Intensive care medicinePurpose Whilst survival in paediatric critical care has improved, clinicians lack tools capable of predicting long-term outcomes. We developed a machine learning model to predict poor school outcomes in children surviving intensive care unit (ICU). Methods Population-based study of children < 16 years requiring ICU admission in Queensland, Australia, between 1997 and 2019. Failure to meet the National Minimum Standard (NMS) in the ...Journal Article -
Serving quarreling masters: Frontline workers and policy implementation under pressure
(2023)GovernanceHow do frontline workers implement policy when it is politically contested and they face strong pressure from politicians and the media? Based on original data and a multi-method analysis of juvenile justice policy and child protection policy in Switzerland, we show that political conflict can change policy implementation when frontline workers adapt their implementation practices in response to political and media pressure. We demonstrate ...Journal Article -
Pathogenic SCN2A variants cause early-stage dysfunction in patient-derived neurons
(2023)Human Molecular GeneticsPathogenic heterozygous variants in SCN2A, which encodes the neuronal sodium channel Na(V)1.2, cause different types of epilepsy or intellectual disability (ID)/autism without seizures. Previous studies using mouse models or heterologous systems suggest that Na(V)1.2 channel gain-of-function typically causes epilepsy, whereas loss-of-function leads to ID/autism. How altered channel biophysics translate into patient neurons remains unknown. ...Journal Article -
Four Decades of Trends and Drivers of Global Surface Ocean Acidification
(2023)Global Biogeochemical CyclesThe oceans are acidifying in response to the oceanic uptake of anthropogenic carbon dioxide (CO2) from the atmosphere, yet the global-scale progression of this acidification has been poorly documented so far by observations. Here, we fill this gap and use an updated version of the in situ and satellite observation-based product OceanSODA-ETHZ to determine the trends and drivers of the surface ocean aragonite saturation state (Ωar) and ...Journal Article -
Robust cooperative train trajectory optimization with stochastic delays under virtual coupling
(2023)IET Intelligent Transport SystemsVirtual coupling technology was recently proposed in railways, which separates trains by a relative braking distance (or even shorter distance) and moves trains synchronously to increase capacity at bottlenecks. This study proposes a real-time cooperative train trajectory planning algorithm for coordinating train movements under virtual coupling by considering stochastic initial delays. The algorithm uses mixed-integer programming models ...Journal Article -
Temperature Calibration of Elevated Mg/Ca in Planktic Foraminifera Shells From the Hypersaline Gulf of Aqaba
(2023)Geochemistry, Geophysics, GeosystemsThe Mg/Ca of marine calcareous Planktic Foraminifera (PF) shells is commonly used for sea surface temperature reconstructions. However, compared to open marine environments, hypersaline (>40) oligotrophic seas have been shown to accommodate PF with higher Mg/Ca and divergent temperature to Mg/Ca relationships. To investigate influencing factors of PF Mg uptake in hypersaline regions, we measured the Mg/Ca of two flux-dominating PF species, ...Journal Article