Living in a bubble: On chip monitoring of microbial production in lipid vesicles
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Autor(in)
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Datum
2019Typ
- Other Conference Item
ETH Bibliographie
yes
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Abstract
We present a novel microbial cultivation strategy combined with a microfluidic platform for real-time monitoring of microbial growth and production. Escherichia coli overexpressing the riboflavin (vitamin B2) biosynthetic pathway is encapsulated in giant lipid vesicles (GUVs) and cultivated on-chip. The behavior of cultures under optimum conditions and under antibiotic stress are compared. Mehr anzeigen
Publikationsstatus
publishedBuchtitel
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019)Seiten / Artikelnummer
Verlag
Chemical and Biological Microsystems SocietyKonferenz
Thema
Antibiotics; Microbial cultivation; Single-cell analysisOrganisationseinheit
03807 - Dittrich, Petra / Dittrich, Petra
Förderung
167123 - Microfluidic device for ultrarapid phenotypic susceptibility testing of pathogenic microbes (SNF)
681587 - Engineering of hybrid cells using lab-on-chip technology (EC)
Anmerkungen
Poster presentation W023.aETH Bibliographie
yes
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