Characterization and spontaneous induction of urinary tract Streptococcus anginosus prophages
Open access
Datum
2020Typ
- Journal Article
ETH Bibliographie
no
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Abstract
Streptococcus anginosus is an often overlooked and understudied emerging pathogen inhabiting many areas of the human body. Through our sequencing of S. anginosus strains isolated from the female bladder microbiota, we detected numerous prophage sequences. Bioinformatic analysis of these sequences identified 17 distinct groups of S. anginosus prophages. The majority of these phages exhibit no sequence homology to previously characterized temperate or virulent phage sequences, indicating an unexplored diversity of Streptococcus phages. By culturing these bacterial isolates, we confirmed that the prophages of five of these groups are capable of induction. One of these putative phages was imaged, the first such evidence of an S . anginosus virus-like particle; it exhibits morphological characteristics of siphoviruses. Mehr anzeigen
Persistenter Link
https://doi.org/10.3929/ethz-b-000451912Publikationsstatus
publishedExterne Links
Zeitschrift / Serie
Journal of General VirologyBand
Seiten / Artikelnummer
Verlag
Microbiology SocietyThema
Streptococcus anginosus; Bacteriophage; Urinary tractOrganisationseinheit
02520 - Institut für Mikrobiologie / Institute of Microbiology
ETH Bibliographie
no
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