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Intensity-modulated proton therapy treatment delivery of locally advanced non-small-cell lung cancers within a single breath-hold
(2021)Objective: We studied the feasibility of pencil beam scanning (PBS) proton therapy treatments within a single breath-hold at PSI’s Gantry 2. Treatment delivery time in PBS proton therapy depends on beam-on time and the dead time between proton spots (time required to change energy and/or lateral position). We studied ways to reduce beam-on and lateral scanning time, without sacrificing dosimetric plan quality, aiming at a single field ...Conference Poster -
Feasibility study to achieve hypofractionated proton therapy within a single breath- hold for lung cancer
(2021)Conference Poster -
Use of momentum cooling to achieve flash dose-rates even for low-energy beams in cyclotron-based proton therapy facilities
(2022)Background and Aims: In proton therapy, the potential high dose-rates (FLASH) for cancer treatment is currently being explored. If performed with cyclotrons however, energy degradation is required. If performed upstream (using a degrader plus and energy/momentum selection system (ESS)), large beam losses result, whilst if performed downstream, just before the patient, the beam width is substantially compromised. In both cases, the net ...Conference Poster -
A novel energy selection system to achieve FLASH dose-rates even for low-energy beams in cyclotron-based proton therapy facilities
(2022)In proton therapy, the potential of ultra-high (FLASH) dose-rate for cancer treatment is being explored due to its potential for enhancing biological effect, faster hypo-fractionated treatments and for efficient motion mitigation. However, energy degradation for FLASH irradiations using cyclotrons is far from optimal; if performed upstream (as common clinically, using a degrader plus an energy/momentum selection system, or ESS), very large ...Conference Poster