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Recently Added
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Leveraging relaxation-optimized <SUP>1</SUP>H-<SUP>13</SUP>C<sub>F</sub> correlations in 4-<SUP>19</SUP>F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins
(2025)Nature ChemistryNMR spectroscopy of biomolecules provides atomic level information into their structure, dynamics and interactions with their binding partners. However, signal attenuation from line broadening caused by fast relaxation and signal overlap often limits the application of NMR to large macromolecular systems. Here we leverage the slow relaxation properties of 13C nuclei attached to 19F in aromatic 19F-13C spin pairs as well as the spin-spin ...Journal Article -
Gaussian mixture autoencoder for uncertainty-aware damage identification in a floating offshore wind turbine
(2025)WIND ENERGY SCIENCEThis work proposes an uncertainty-aware approach to the inverse problem of damage identification in a floating offshore wind turbine (FOWT). We design an autoencoder architecture, where the latent space represents the features of the target damage condition. The inverse operator (encoder) is a deep neural network that maps the measurable response to the parameters (means, variances, and weights) of a multivariate Gaussian mixture model. ...Journal Article -
Boundary Conditions and Violations of Bulk-Edge Correspondence in a Hydrodynamic Model
(2025)Annales Henri PoincaréBulk-edge correspondence is a wide-ranging principle that applies to topological matter, as well as a precise result established in a large and growing number of cases. According to the principle, the distinctive topological properties of matter, thought of as extending indefinitely in space, are equivalently reflected in the excitations running along its boundary, when one is present. Indices encode those properties, and their values, ...Journal Article -
Chemical Synthesis and Chaperone Peptide Mediated Folding of Human Nerve Growth Factor by Expressed KAHA Ligation
(2025)ACS CENTRAL SCIENCENerve growth factor (NGF) is a powerful neurotrophic protein for treating central nervous system diseases, but its therapeutic utility is limited by severe side effects, including hyperalgesia. These adverse effects arise from pleitropic receptor binding that can, in principle, be modulated by side chain mutations or modification-a task suited for chemical protein synthesis. Despite its small size (13 kDa), the chemical synthesis of NGF ...Journal Article -
Drought decreases carbon flux but not transport speed of newly fixed carbon from leaves to sinks in a giant bamboo forest
(2025)Journal of EcologyCarbon (C) allocation among different plant tissues is crucial for maintaining C balance in forest ecosystems, especially under changing climate conditions. The partitioning of newly assimilated C among plant tissues, interconnected ramets and soil in forests dominated by giant clonal plants, such as moso bamboo (Phyllostachys edulis), and the influence of drought on this partitioning remain poorly understood. In August 2019, we performed ...Journal Article