1. Quantitative analysis of yeast MAPK signaling networks and crosstalk using a microfluidic device 

   Lee, Byungjin; Jeong, Seong-Geun; Jin, Si Hyung; et al. (2020)

   Lab on a Chip

   Eukaryotic cells developed complex mitogen-activated protein kinase (MAPK) signaling networks to sense their intra- and extracellular environment and respond to various stress conditions. For example,S. cerevisiaeuses five distinct MAP kinase pathways to orchestrate meiosis or respond to mating pheromones, osmolarity changes and cell wall stress. Although each MAPK module has been studied individually, the mechanisms underlying crosstalk ...

   Journal Article

2. Elongation Patterns of the Posterior Cruciate Ligament after Total Knee Arthroplasty 

   Nasab, Seyyed Hamed Hosseini; Smith, Colin; Schutz, Pascal; et al. (2020)

   JOURNAL OF CLINICAL MEDICINE

   This study aimed to understand the ability of fixed-bearing posterior cruciate ligament (PCL)-retaining implants to maintain functionality of the PCL in vivo. To achieve this, elongation of the PCL was examined in six subjects with good clinical and functional outcomes using 3D kinematics reconstructed from video-fluoroscopy, together with multibody modelling of the knee. Here, length-change patterns of the ligament bundles were tracked ...

   Journal Article

3. One of the earliest refractory inclusions and its implications for solar system history 

   Bodénan, Jean-Dabid; Starkey, Natalie A.; Russell, Sara S.; et al. (2020)

   Geochimica et Cosmochimica Acta

   A ∼175 µm refractory inclusion, A-COR-01 from one of the least altered carbonaceous chondrites, ALHA 77307 (CO3.0), has been found to bear unique characteristics that indicate that it is one of the first solids to have formed at the very birth of the solar system while isotopic reservoirs were still evolving rapidly. Its core is composed mainly of hibonite and corundum, the two phases predicted to condense first from a gas of solar ...

   Journal Article

4. Lateral stability in healthy proximal interphalangeal joints versus surface replacement and silicone arthroplasty: Results of a three-dimensional motion analysis study 

   Hensler, Stefanie; Behm, Pascal; Wehrli, Martina; et al. (2020)

   Hand Surgery and Rehabilitation

   The objective of this study was to quantify the lateral stability of healthy proximal interphalangeal (PIP) joints using a three-dimensional motion capture system and compare it to affected joints after surface replacement or silicone arthroplasty. Three study groups comprised healthy participants, patients with PIP joint osteoarthritis treated with a surface replacing implant (CapFlex-PIP) and those with a silicone arthroplasty. All ...

   Journal Article

5. Non-isothermal flow between heated building models 

   Tsalicoglou, Christina; Allegrini, Jonas M.; Carmeliet, Jan C. (2020)

   Journal of Wind Engineering and Industrial Aerodynamics

   The Urban Heat Island Effect describes the phenomenon that urban areas are typically warmer than the nearby rural areas, as the presence of the city causes an increase in air temperature. Increased temperatures in urban environments lead to increased discomfort, health problems, and higher cooling demands. It is therefore essential to be able to predict the location where higher temperatures tend to occur and to propose mitigation strategies ...

   Journal Article

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