1. Warm-air entrainment and advection during alpine blowing snow events 

   Aksamit, Nikolas O.; Pomeroy, John W. (2020)

   The Cryosphere

   Blowing snow transport has considerable impact on the hydrological cycle in alpine regions both through the redistribution of the seasonal snowpack and through sublimation back into the atmosphere. Alpine energy and mass balances are typically modeled with time-averaged approximations of sensible and latent heat fluxes. This oversimplifies nonstationary turbulent mixing in complex terrain and may overlook important exchange processes for ...

   Journal Article

2. SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation 

   Schubert, Katharina; Karousis, Evangelos D.; Jomaa, Ahmad; et al. (2020)

   Nature Structural & Molecular Biology

   The SARS-CoV-2 non-structural protein 1 (Nsp1), also referred to as the host shutoff factor, suppresses host innate immune functions. By combining cryo-electron microscopy and biochemistry, we show that SARS-CoV-2 Nsp1 binds to the human 40S subunit in ribosomal complexes, including the 43S pre-initiation complex and the non-translating 80S ribosome. The protein inserts its C-terminal domain into the mRNA channel, where it interferes with ...

   Journal Article

3. Warm-air entrainment and advection during alpine blowing snow events 

   Aksamit, Nikolas O.; Pomeroy, John W. (2020)

   The Cryosphere

   Blowing snow transport has considerable impact on the hydrological cycle in alpine regions both through the redistribution of the seasonal snowpack and through sublimation back into the atmosphere. Alpine energy and mass balances are typically modeled with time-averaged approximations of sensible and latent heat fluxes. This oversimplifies nonstationary turbulent mixing in complex terrain and may overlook important exchange processes for ...

   Journal Article

4. Interplay of spin waves and vortices in the two-dimensional XY model at small vortex-core energy 

   Maccari, I; Defenu, N.; Benfatto, L.; et al. (2020)

   Physical Reiew B

   The Berezinskii-Kosterlitz-Thouless (BKT) mechanism describes universal vortex unbinding in many two-dimensional systems, including the paradigmatic XY model. However, most of these systems present a complex interplay between excitations at different length scales that complicates theoretical calculations of nonuniversal thermodynamic quantities. These difficulties may be overcome by suitably modifying the initial conditions of the BKT ...

   Journal Article

5. Combining the best interest standard with shared decision-making in paediatrics - introducing the shared optimum approach based on a qualitative study 

   Streuli, Jurg Caspar; Anderson, James; Alef-Defoe, Sierra; et al. (2020)

   European journal of pediatrics

   Paediatric decision-making is the art of respecting the interests of child and family with due regard for evidence, values and beliefs, reconciled using two important but potentially conflicting concepts: best interest standard (BIS) and shared decision-making (SD-M). We combine qualitative research, our own data and the normative framework of the United Nations Convention on the Rights of Children (UNCRC) to revisit current theoretical ...

   Journal Article

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