1. Nanopore Deep Sequencing as a Tool to Characterize and Quantify Aberrant Splicing Caused by Variants in Inherited Retinal Dystrophy Genes 

   Maggi J.; Feil S.; Gloggnitzer J.; et al. (2024)

   International Journal of Molecular Sciences

   The contribution of splicing variants to molecular diagnostics of inherited diseases is reported to be less than 10%. This figure is likely an underestimation due to several factors including difficulty in predicting the effect of such variants, the need for functional assays, and the inability to detect them (depending on their locations and the sequencing technology used). The aim of this study was to assess the utility of Nanopore ...

   Journal Article

2. CALDERA: a scientific drilling concept to unravel Connections Among Life, geo-Dynamics and Eruptions in a Rifting Arc caldera, Okataina Volcanic Centre, Aotearoa New Zealand 

   Massiot C.; Adam L.; Boyd E.S.; et al. (2024)

   Scientific drilling

   Silicic caldera volcanoes present major volcanic and seismic hazards but also host dynamic hydrothermal and groundwater systems and a rich but largely unexplored subsurface biosphere. Many of these volcanoes are hosted in rift settings. The intricate connections and feedbacks among magmatism, rifting, hydrothermal processes, and the biosphere in these complex systems remain poorly understood, necessitating subsurface joint observations ...

   Conference Paper

3. Crustal carbonate build-up as a driver for Earth's oxygenation 

   Alcott, Lewis J.; Walton, Craig; Planavsky, Noah J.; et al. (2024)

   Nature Geoscience

   Oxygenation of Earth's atmosphere and oceans played a pivotal role in the evolution of the surface environment and life. It is thought that the rise in oxygen over Earth's history was driven by an increasing availability of the photosynthetic limiting nutrient phosphate combined with declining oxygen-consuming inputs from the mantle and crust. However, it has been difficult to assess whether these processes alone can explain Earth's ...

   Journal Article

4. Deep CO₂ release and the carbon budget of the central Apennines modulated by geodynamics 

   Erlanger, Erica; Bufe, Aaron; Paris, Guillaume; et al. (2024)

   Nature Geoscience

   Recent studies increasingly recognize the importance of critical-zone weathering during mountain building for long-term CO2 drawdown and release. However, the focus on near-surface weathering reactions commonly does not account for CO2 emissions from the crust, which could outstrip CO2 drawdown where carbonates melt and decarbonize during subduction and metamorphism. We analyse water chemistry from streams in Italy's central Apennines ...

   Journal Article

5. Analyzing the extent and use of impervious land in rural landscapes 

   Moser, Andreas; Van Vliet, Jasper; Wissen Hayek, Ulrike; et al. (2024)

   Geography and Sustainability

   The amount of impervious surface is increasing rapidly worldwide. Although urban expansion has been studied extensively, the alteration of impervious land cover in rural regions remains under-examined. In particular, insights into the utilization of these sealed surfaces are crucially needed to unravel the underlying dynamics of land use changes beyond urban areas. This study focuses on rural regions from a Swiss case study and presents ...

   Journal Article

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