1. Differences Between Trial Populations and Approved Label Populations of New Drugs in the United States and Europe (2012 to 2023): A Cross-Sectional Study 

   Vokinger, Kerstin N.; Serra-Burriel, Miquel; Glaus, Camille E. G.; et al. (2025)

   Annals of internal medicine

   Background: Drugs are approved when their benefits outweigh their risks based on the results of clinical trials. It remains unclear how often regulatory agencies extrapolate or restrict the approval compared with the trial. Objective: To analyze the differences in the characteristics of enrolled patients between trial populations and approved label populations in the United States, European Union (EU), and Switzerland for new drugs. Design: ...

   Journal Article

2. MINDS: The very low-mass star and brown dwarf sample: Detections and trends in the inner disk gas 

   Arabhavi, A. M.; Kamp, I.; Henning, Th.; et al. (2025)

   Astronomy & Astrophysics

   Context. Planet-forming disks around brown dwarfs and very low-mass stars (VLMS) are, on average, less massive and are expected to undergo faster radial solid transport than their higher-mass counterparts. Spitzer had detected C2H2, CO2, and HCN around these objects but did not provide a firm detection of water. With a better sensitivity and spectral resolving power than that of Spitzer, the James Webb Space Telescope (JWST) has recently ...

   Journal Article

3. Experimental Assessment of a Counter-Current Particle-Air Solar Receiver 

   Hartner, Anton; Gunti, Dario; Steinfeld, Aldo; et al. (2025)

   The design of a counter current particle-air solar receiver is proposed and its performance investigated at the laboratory scale. Its design consists of a silicon carbide (SiC) tube with an internal diameter of 19.5 mm, enclosed by a solar cavity of rectangular prism in geometry with internal dimensions of approximately 55 mm x 55 mm x 200 mm. The solar cavity contains a 40 mm diameter circular aperture for the access of concentrated ...

   Other Conference Item

4. Structural Dynamics Behind the Formation of α′-Ni₃Ga Alloy Nanoparticles from a Ni-Ga Phyllosilicate Dispersed on Silica Using X-ray Probes 

   Zimmerli, Nora K.; Piankova, Diana; Kierzkowska, Agnieszka; et al. (2025)

   Chemistry of Materials

   This study investigates the structural evolution during the formation of alpha '-Ni3Ga alloy nanoparticles from Ni-Ga phyllosilicate sheets upon heating in H2. The phyllosilicate sheets were produced through a deposition-precipitation process using Ni and Ga nitrates and colloidal SiO2. Advanced characterization techniques, including X-ray absorption spectroscopy, pair distribution function analysis, and electron microscopy, revealed the ...

   Journal Article

5. Murbeckiella is dead, long live Oreophyton: origin and systematics of tribe Oreophytoneae (Brassicaceae) 

   Walden, Nora; Mansion, Guilhem; Schnorf, Hektor; et al. (2025)

   Annals of Botany

   Background and Aims The small genus Murbeckiella from the Brassicaceae family underwent manifold taxonomic changes reflecting morphological uncertainties, but also unusual biogeographical distribution patterns ranging from Spain and northern Africa to Caucasus. Close relationships with Oreophyton have been proposed, and both genera have been placed in the orphan tribe Oreophytoneae. We explore phylogenetic relationships to unravel and ...

   Journal Article

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