Search
Results
-
Local Arp2/3 dependent actin assembly modulates applied traction force during apCAM adhesion site maturation
(2017)Molecular Biology of the CellHomophilic binding of immunoglobulin superfamily molecules such as the Aplysia cell adhesion molecule (apCAM) leads to actin filament assembly near nascent adhesion sites. Such actin assembly can generate significant localized forces that have not been characterized in the larger context of axon growth and guidance. We used apCAM-coated bead substrates applied to the surface of neuronal growth cones to characterize the development of ...Journal Article