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Hybrid-Electric Vehicle with Natural Gas-Diesel Engine
(2013)EnergiesAbstract In this paper we demonstrate the potential of combining electric hybridization with a dual-fuel natural gas-Diesel engine. We show that carbon dioxide emissions can be reduced to 43 gram per kilometer with a subcompact car on the New European Driving Cycle (NEDC). The vehicle is operated in charge-sustaining mode, which means that all energy is provided by the fuel. The result is obtained by hardware-in-the-loop experiments where ...Journal Article -
Intake Manifold Boosting of Turbocharged Spark-Ignited Engines
(2013)EnergiesDownsizing and turbocharging is a widely used approach to reduce the fuel consumption of spark ignited engines while retaining the maximum power output. However, a substantial loss in drivability must be expected due to the occurrence of the so-called turbo lag. The turbo lag results from the additional inertia that the turbocharger adds to the system. Supplying air by an additional valve, the boost valve, to the intake manifold can be ...Journal Article -
Fracturing ranked surfaces
(2012)Scientific ReportsDiscretized landscapes can be mapped onto ranked surfaces, where every element (site or bond) has a unique rank associated with its corresponding relative height. By sequentially allocating these elements according to their ranks and systematically preventing the occupation of bridges, namely elements that, if occupied, would provide global connectivity, we disclose that bridges hide a new tricritical point at an occupation fraction p = ...Journal Article -
Combined Optimal Sizing and Control for a Hybrid Tracked Vehicle
(2012)EnergiesThe optimal sizing and control of a hybrid tracked vehicle is presented and solved in this paper. A driving schedule obtained from field tests is used to represent typical tracked vehicle operations. Dynamics of the diesel engine-permanent magnetic AC synchronous generator set, the lithium-ion battery pack, and the power split between them are modeled and validated through experiments. Two coupled optimizations, one for the plant parameters, ...Journal Article -
The bee microbiome: Impact on bee health and model for evolution and ecology of host-microbe interactions
(2016)mBioAs pollinators, bees are cornerstones for terrestrial ecosystem stability and key components in agricultural productivity. All animals, including bees, are associated with a diverse community of microbes, commonly referred to as the microbiome. The bee microbiome is likely to be a crucial factor affecting host health. However, with the exception of a few pathogens, the impacts of most members of the bee microbiome on host health are poorly ...Journal Article -
Cyclic Diguanylate Signaling Proteins Control Intracellular Growth of Legionella pneumophila
(2011)mBioProteins that metabolize or bind the nucleotide second messenger cyclic diguanylate regulate a wide variety of important processes in bacteria. These processes include motility, biofilm formation, cell division, differentiation, and virulence. The role of cyclic diguanylate signaling in the lifestyle of Legionella pneumophila, the causative agent of Legionnaires’ disease, has not previously been examined. The L. pneumophila genome encodes ...Journal Article -
Screening of Escherichia coli species biodiversity reveals new biofilm-associated antiadhesion polysaccharides
(2011)mBioBacterial biofilms often form multispecies communities in which complex but ill-understood competition and coop-eration interactions occur. In light of the profound physiological modifications associated with this lifestyle, we hypothesizedthat the biofilm environment might represent an untapped source of natural bioactive molecules interfering with bacterial adhe-sion or biofilm formation. We produced cell-free solutions extracted fromin ...Journal Article -
The relationship between metastatic potential and in vitro mechanical properties of osteosarcoma cells
(2019)Molecular Biology of the CellOsteosarcoma is the most frequent primary tumor of bone and is characterized by its high tendency to metastasize in lungs. Although treatment in cases of early diagnosis results in a 5-yr survival rate of nearly 60%, the prognosis for patients with secondary lesions at diagnosis is poor, and their 5-yr survival rate remains below 30%. In the present work, we have used a number of analytical methods to investigate the impact of increased ...Journal Article -
Dissociation of membrane–chromatin contacts is required for proper chromosome segregation in mitosis
(2019)Molecular Biology of the CellJournal Article -
Fingerprinting Breast Cancer vs. Normal Mammary Cells by Mass Spectrometric Analysis of Volatiles
(2014)Scientific ReportsThere is increasing interest in the development of noninvasive diagnostic methods for early cancer detection, to improve the survival rate and quality of life of cancer patients. Identification of volatile metabolic compounds may provide an approach for noninvasive early diagnosis of malignant diseases. Here we analyzed the volatile metabolic signature of human breast cancer cell lines versus normal human mammary cells. Volatile compounds ...Journal Article