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A Pipeline for Personalized Brain Modeling: From Stimulation to Network Activity
(2023)BioEM 2023 - Abstract CollectionNeurological and psychiatric disorders are the leading cause of disability worldwide. Personalized computational modeling is a powerful method for probing whole brain network dynamics in both health and disease, and for creating optimized brain stimulation-based therapies. To this end, we developed an automated patient-specific modeling pipeline starting from structural magnetic resonance imaging (MRI) scans, and resulting in a 16 tissue, ...Other Conference Item -
Computational modelling for non-invasive monitoring of intracranial pressure
(2023)7th HBP Student Conference on Interdisciplinary Brain Research. Book of AbstractsMeasuring intracranial pressure (ICP) is crucial for diagnosis, treatment and monitoring of craniospinal disorders. Non-invasive ICP measurement is still a grand challenge despite more than 60 years of research. In this study, we tackle this challenge by computing the head impedance changes (∆Z) during the cardiac cycles inspired by the work of Russegger and Ennemoser. We use the results to establish correlations between the non-invasively ...Other Conference Item -
Towards a non-invasive craniospinal compliance biomarker
(2022)Measuring intracranial pressure (ICP) is required for clinical management of several neurological disorders. Of arguably similar value, but more difficult to measure, is craniospinal compliance (CC). Changes in head impedance due to geometry and dielectric properties variation during the cardiac cycle is a promising biomarker for non-invasive CC monitoring. Recently, we developed an efficient computational method to facilitate signal ...Other Conference Item -
Computational analysis for non-invasive acquisition of craniospinal compliance
(2021)Diagnosis, treatment, and monitoring of patients suffering from craniospinal diseases requires the measurement of intracranial pressure (ICP). Several measurement methods have been developed, but currently only invasive techniques are sufficiently reliable to be clinically accepted. As brain geometry and dielectric properties are transiently modulated by blood and cerebrospinal fluid exchange between cranial and spinal compartments, ...Other Conference Item -
Computational models steering the personalization of targeted spinal cord stimulation to restore motor function in humans with spinal cord injury
(2018)Neuroscience 2018 AbstractsOther Conference Item -
Towards Multiscale Modeling of Transcranial Focused Ultrasound Neurostimulation
(2018)Other Conference Item -
Multiscale, Personalized Modeling of Blood-Flow-Related Vessel-Wall Evolution
(2017)Abstract Book: 3rd International SystemsX.ch Conference on Systems Biology, September 4 – 7, 2017, ETH Zurich, SwitzerlandOther Conference Item -
Optimization of Targeted Neurostimulation Based on Activating Functions and Validation by Coupled Electromagnetic-Neuronal Dynamics Modelling
(2017)The Joint Meeting of the Bioelectromagnetics Society (BEMS) and the European BioElectromagnetics Association (EBEA): Technical Program and General InformationOther Conference Item