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Allosteric Inhibitors of the Enzyme IspD of the Non-Mevalonate Pathway for Isoprenoid Biosynthesis
(2017)Malaria is a major burden and cause of death in developing contries with over 200 million cases reported worldwide each year. The emergence of multi drug resistant malaria parasites, in particular against the widely used artemisinin based therapy, requires a timely response. The development of drugs with new modes of action is among the most efficient ways in combating resistance and necessitates the exploartion of new molecular targets ...Doctoral Thesis -
Numerical Modeling of Morphological Response of Gravel-Bed Rivers to Sediment Supply
(2017)Doctoral Thesis -
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Clustering of phoretic and inertial particles in uniform and non-uniform turbulence
(2017)Doctoral Thesis -
Potential Vorticity Diagnostics to Quantify Effects of Latent Heating in Extratropical Cyclones: Methodology and Application to Idealized Climate Change Simulations
(2017)Extratropical cyclones develop due to baroclinic instability, but their intensification is often substantially amplified by diabatic processes, most importantly latent heating (LH) through cloud formation. Although this amplification is well understood for individual cyclones, there is still need for a systematic and quantitative investigation of how LH affects cyclone intensification in different, particularly warmer and moister climates ...Doctoral Thesis -