Theses
Lower-level publication types
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Bachelor Thesis [57]
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Doctoral Thesis [26753]
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Habilitation Thesis [162]
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Master Thesis [1420]
Recent Submissions
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Cross-linking methods to identify the mRNA targets of microRNAs
(2020)microRNAs (miRNAs, miRs) constitute a class of small, endogenous, non-coding RNAs (ncRNAs) and have a great influence on various processes within the cell. By base‐pairing selectively to partially‐complementary sites located predominantly in the 3′-untranslated region (3′‐UTR) of target messenger RNAs (mRNAs), miRNAs participate in the post-transcriptional regulation of gene expression. miRNAs are responsible for controlling the expression ...Doctoral Thesis -
Ground-up construction of a bioproduction locus for protein expression in mammalian cells
(2020)Protein-based therapeutics, ranging from antibodies to growth hormones, represent an important class of pharmaceuticals. Recombinant DNA technologies massively expedited the process of large-scale protein manufacturing and allowed to add molecules that do not occur in nature - such as fusion proteins - to the arsenal of medicine. Large proteins and proteins that require complex post-translational modifications are normally produced in ...Doctoral Thesis -
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FeatPredict: Feature-based Trajectory Prediction in Regulated Urban Traffic
(2020)One of the main challenges for the ultimate deployment of level 5 full driving automated vehicles is a safe, reliable and efficient motion planning framework which needs to take into account the possible interactions with other road agents. For this, it is crucial for the autonomous vehicle to have some ability to reason about the future motion of surrounding vehicles. The future trajectory of a road agent is influenced by the relative ...Master Thesis -
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Evolutionary and population genomics of the wheat pathogen Parastagonospora nodorum
(2020)Food production is continuously under threat by plant pathogens. In the agricultural system, pathogen populations are under high selection pressure, and yet demonstrate high adaptive potential to overcome changing conditions. The genetic variation and genomic mechanisms underpinning the fast evolutionary rates in pathogen populations are poorly understood. In this thesis, I studied the genetic basis of adaptation in populations of ...Doctoral Thesis -
Machine learning on molecular networks to decipher the genetics underlying complex traits
(2020)Doctoral Thesis -
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Give us a break!
(2020)Erforschung der Sozialgeschichte des Schweizer Designs, die in den lebensweltlichen und biografischen Brüchen von sozialen Aufsteiger*innen aus Arbeitermilieus ins Zürcher Designfeld während der Ära des Neoliberalismus manifest wird.Doctoral Thesis -
Computational Design Synthesis for the Co-Design of Morphology and Actuation of Soft Robots for Locomotion
(2020)Compliant robots, i.e. robots that yield to external forces, have advantages compared to rigid robots in several respects. In direct contact with humans, compliant robots are safer. They can also compensate for imperfect perception of the environment. For example, a compliant gripper can achieve an even force distribution when holding a tomato without knowing the exact shape of the tomato. Soft robots are compliant robots that achieve ...Doctoral Thesis -
Hygromechanics and Shape Memory of Wood Cell Wall Investigated with Multiscale Modeling
(2020)Wood is an important material for mankind, not only because of its profound impact on the industry and everyday life, but also for its enormous potential for providing sustainable solutions to futuristic, advanced materials. One crucial characteristic of wood is the strong hygroscopicity. When subjected to moisture, a series of mechanical and physical phenomena are induced, such as swelling, weakening and shape memory effect, the fundamental ...Doctoral Thesis -
Model-supported Improvement of Stability Limit Predictions in Milling Through Artificial Neural Networks
(2020)Stability lobe diagrams are a well-known method to differentiate stable from unstable cutting conditions and to indicate stability pockets with high productivity in milling. Unstable process conditions lead to self-excited vibrations between the tool and the workpiece, so-called chatter vibrations, which have highly negative consequences such as reduced machine and tool lifetimes and deteriorated workpiece surface qualities. The creation ...Doctoral Thesis -
Fostering Sustainability Using Information Technology: Real-Time Feedback, Incentives, and Smart Markets
(2020)Despite growing public attention and policy efforts for environmental sustainability, world-wide energy consumption and greenhouse gas emissions are still increasing (International Energy Agency, 2020a). Technological advances have enabled improvements in energy efficiency, and hundreds of billions of US dollars are being invested in renewable energy generation every year (International Energy Agency, 2020a), however, actually implement- ...Doctoral Thesis -
The root rot complex of pea - Screening for resistance and quantification of microbial key players in the rhizosphere
(2020)Pea (Pisum sativum L.) is a valuable and healthy protein source for food and feed. In addition to the nutritional benefits, pea is an invaluable agro-ecological asset for sustainable cropping systems through positive effects on soil fertility and soil microbial diversity. The symbiosis with nitrogen-fixing bacteria allows pea and other legume crops to supply the soil with nitrogen and, therefore, to significantly reduce the application ...Doctoral Thesis -
Die philosophische Schnecke. In der Philosophie gewinnt, wer als letzter ankommt.
(2020)(en) In my PhD thesis I interpret the philosophy of Ludwig Wittgenstein as a critique of culture. This critique stands in the Socratic tradition of thinking which pursues caring for successful conduct of life as its the central theme. Understood in this Socratic way, philosophy is an ethical endeavor which has to always be measured against its value for a meaningful life. In strong contrast, Wittgenstein’s philosophy is very often seen ...Doctoral Thesis -