Recent Submissions 

  1. Collaborations between startups and established firms: Intellectual property protection and engagement programs 

    Fink, Alexander Albert (2022)
    Collaborations between startups and established firms are a double-edged sword – they hold enormous potential for value creation, but can lead to value misappropriation. In this dissertation, I examine two critical factors which determine the value creation and appropriation in such collaborations: (1) identifying suitable collaborators and (2) misappropriation of startups’ intellectual property (IP). The following three essays, which ...
    Doctoral Thesis
  2. Beyond reproducibility: Knocking on sustainability's door 

    Jablonski, Kim Philipp (2022)
    The following thesis presents three independent studies which were carried out as part of the author's doctoral studies in the Computational Biology Group at the Department of Biosystems Science and Engineering at ETH Zurich in Basel. These projects deal with the development of statistical methods for the detection of pathway dysregulations, and the processing and analysis of next-generation sequencing data with a particular focus on the ...
    Doctoral Thesis
  3. High repetition rate soft X-ray sources from few-cycle OPCPAs 

    Chevreuil, Pierre-Alexis (2022)
    Attosecond science studies the fastest dynamics of matter, revealing how physical and chemical processes take place at the most fundamental level. A spectral region of particular interest for the generation of attosecond pulses is in the soft X-rays, between 283 and 543 eV. Indeed, attosecond pulses generated in this so-called water window can be used to study biological samples at the electronic time scale (10^(−15) to 10^(-18) ...
    Doctoral Thesis
  4. Development of a microfluidic platform to emulate the human microvasculature 

    Hirth, Elisabeth F. (2022)
    The human body employs a tube-like system calledblood vessels for transporting molecules such as oxygen or cells. These pipes are lined with endothelial cells that are phenotypically different and thus very heterogenous. Due to its important role in maintaining homeostasis, every organ and tissue is heavily relying on thorough vascularization. Thus, with intravenous drug administration every target within the ...
    Doctoral Thesis
  5. Higher Order Mass Map Statistics for Wide Field Weak Lensing Surveys 

    Zürcher, Dominik (2022)
    Doctoral Thesis
  6. Synthetic biology circuits: temperature and myocardial infarction sensors for precision therapeutics 

    Stefanov, Bozhidar-Adrian (2022)
    Personalized medicine is the science for developing remedies tailored to the individual necessities of each and every patient. The regulatory approval of the first engineered mammalian cell therapies enhanced the anticipation that these are to become the next pillar of medical care for complex and chronic disease. Although such cells are biological entities, they are modified using engineering principles in what is now established as the ...
    Doctoral Thesis
  7. Biomedical Signal Analysis of the Brain and Systemic Physiology 

    Guglielmini, Sabino (2022)
    Near-infrared spectroscopy (NIRS) is a non-invasive and easy-to-use diagnostic technique that enables real-time tissue oxygenation measurements applied in various contexts and for different purposes. Continuous monitoring with NIRS of brain oxygenation, for example, in neonatal intensive care units (NICUs), is essential to prevent lifelong disabilities in newborns. Moreover, NIRS can be applied to observe brain activity associated with ...
    Doctoral Thesis
  8. Green state investment banks: Their role in mobilising finance to accelerate the energy transition and the politics behind their establishment and design 

    Geddes, Anna (2020)
    The adoption of the Paris Agreement in 2015 signified a shift away from the Kyoto Protocol’s international burden-sharing outlook towards nationally driven mitigation action, and therefore national level policy tools. Significantly this agreement recognizes the crucial role finance must play in addressing climate change, highlighting the importance of “making finance flows consistent with a pathway towards low greenhouse gas emissions and ...
    Doctoral Thesis
  9. Pathogen phylogenies for public health 

    Nadeau, Sarah (2022)
    An organism’s genome sequence is a rich source of information on its current characteristics and its evolutionary history. In this thesis, I refine and apply methods to extract information from pathogen genome sequences via phylogenetic reconstructions. I extend existing phylogeny-based models to new applications in genome-wide association studies (GWAS) and genomic epidemiology. First, I show that correlations in an infectious disease ...
    Doctoral Thesis
  10. Field-theoretic simulations with advanced interaction potentials 

    Weyman, Alexander (2022)
    Doctoral Thesis
  11. Viscoelastic Flow of Plant Protein Melts under High Moisture Extrusion Conditions 

    Stirnemann, Eric (2022)
    Food Process Engineering series
    Protein is an essential part of our diet and is often consumed in the form of animal products. Raising animals for food emits large amounts of greenhouse gases and is an inefficient way of converting plant protein into food. A less resourceintensive protein supply is needed, to feed a growing population adequately and sustainably. Therefore, an increasing number of consumers choose plant-based meat analogs over traditional animal meat. ...
    Doctoral Thesis
  12. Towards Multiscale Modeling of Ferroelectric Devices 

    Lenarczyk, Pawel (2020)
    Doctoral Thesis
  13. Source apportionment and compositional analysis of organic aerosols in Delhi, India, using novel soft ionization mass spectrometric methods 

    Kumar, Varun (2022)
    In recent decades, urban areas have flourished all across the world. Especially in developing countries such as India, the rapid economic development over the last three decades has led to a large-scale migration from rural to urban areas in search of a better life. Cities such as Delhi have grown in size and population by many times in recent decades. This expansion has been accompanied by large-scale industrialization, an increase in ...
    Doctoral Thesis

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