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Target Identification and Characterization in Transgenic Cardiovascular Disease Models of Atherosclerosis and Heart Failure
(2017)Myocardial infarction and ensuing heart failure are leading causes of death worldwide with limited treatment options. The major aim of my thesis was to identify new pathways involved in the pathogenesis of these diseases, which could be exploited as possible drug targets in the future. Atherosclerosis is the major cause for coronary artery disease and myocardial infarction. Current therapeutic strategies target the atherosclerosis-promoting ...Doctoral Thesis