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Hydrologic predictions in a changing environment: behavioral modeling
(2010)Hydrology and Earth System Sciences DiscussionsMost hydrological models are valid at most only in a few places and cannot be rea-sonably transferred to other places or to far distant time periods. Transfer in space isdifficult because the models are conditioned on past observations at particular placesto define parameter values and unobservable processes that are needed to fully characterize the structure and functioning of the landscape. Transfer in time has to deal withthe likely ...Working Paper -
Electricity Planning for Sustainable Development in the MENA Region
(2017)MENA-SELECT Working PaperWorking Paper -
Development and testing of scenarios for implementing Holocene LULC in Earth System Model Experiments
(2019)Geoscientific Model Development DiscussionsAnthropogenic changes in land use and land cover (LULC) during the pre-industrial Holocene could have affected regional and global climate. Current LULC scenarios are based on relatively simple assumptions and highly uncertain estimates of population changes through time. Archaeological and palaeoenvironmental reconstructions have the potential to refine these assumptions and estimates. The Past Global Changes (PAGES) LandCover6k initiative ...Working Paper -
Species-level microbial sequence classification is improved by source-environment information
(2019)bioRxivPopular naive Bayes taxonomic classifiers for amplicon sequences assume that all species in the reference database are equally likely to be observed. We demonstrate that classification accuracy degrades linearly with the degree to which that assumption is violated, and in practice it is always violated. By incorporating environment-specific taxonomic abundance information, we demonstrate that species-level resolution is attainable.Working Paper -
Revisiting microbe-metabolite interactions: doing better than random
(2019)bioRxivRecently, Quinn and Erb et al [1] made the case that when used correctly, correlation and proportionality can outperform MMvec when identifying microbe-metabolite interactions. We revisit this comparison and show that the proposed correlation and proportionality are outperformed by MMvec on real data due to their inability to deal with sparsity commonly observed in microbiome and metabolome datasets.Working Paper -
Country Fact Sheet Jordan: Energy and Development at a glance 2017: Background Paper
(2017)MENA-SELECT Working PaperWorking Paper -
Sudden cold temperature regulates the time-lag between plant CO2 uptake and release
(2013)Biogeosciences DiscussionsSince substrates for respiration are supplied mainly by recent photo-assimilates, there is a strong but time-lagged link between short-term above- and belowground carbon (C) cycling. However, regulation of this coupling by environmental variables is poorly understood. Whereas recent studies focussed on the effect of drought and shading on the link between above- and belowground short-term C cycling, the effect of temperature remains ...Working Paper -
Lack of evidence that ursodeoxycholic acids effects on the gut microbiome influence colorectal adenoma risk
(2017)bioRxivObjective We previously reported that Ursodeoxycholic acid (UDCA), a therapeutic bile acid, reduces risk for advanced colorectal adenoma in men but not women. Interactions between the gut microbiome and fecal bile acid composition as a factor in colon cancer neoplasia have been postulated but evidence is limited to small cohorts and animal studies. Design Using banked stool samples collected as part of a phase III randomized clinical ...Working Paper -